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Pathogenic variants in human DNA damage repair genes mostly arose in recent human history Journal article
Zhao, Bojin, Li, Jiaheng, Sinha, Siddharth, Qin, Zixin, Kou, Si Hoi, Xiao, Fengxia, Lei, Huijun, Chen, Tianhui, Cao, Wenming, Ding, Xiaofan, Wang, San Ming. Pathogenic variants in human DNA damage repair genes mostly arose in recent human history[J]. BMC Cancer, 2024, 24(1), 415.
Authors:  Zhao, Bojin;  Li, Jiaheng;  Sinha, Siddharth;  Qin, Zixin;  Kou, Si Hoi; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.4/3.8 | Submit date：2024/05/16
Archaeological  Dna Damage Repair  Evolutionary Origin  Pathogenic Variants  Phylogenetic  
Pathogenic variants in human DNA damage repair genes mostly arose after the latest human out-of-Africa migration Journal article
He, Jun, Kou, Si Hoi, Li, Jiaheng, Ding, Xiaofan, Wang, San Ming. Pathogenic variants in human DNA damage repair genes mostly arose after the latest human out-of-Africa migration[J]. Frontiers in Genetics, 2024, 15, 1408952.
Authors:  He, Jun;  Kou, Si Hoi;  Li, Jiaheng;  Ding, Xiaofan;  Wang, San Ming
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:2.8/3.3 | Submit date：2024/08/05
Brca  Ddr Genes  Evolution Origin  Pathogenic Variants  Tp53  
Evolutionary origin of germline pathogenic variants in human DNA mismatch repair genes Journal article
Lei, Huijun, Li, Jiaheng, Zhao, Bojin, Kou, Si Hoi, Xiao, Fengxia, Chen, Tianhui, Wang, San Ming. Evolutionary origin of germline pathogenic variants in human DNA mismatch repair genes[J]. Human Genomics, 2024, 18(1), 5.
Authors:  Lei, Huijun;  Li, Jiaheng;  Zhao, Bojin;  Kou, Si Hoi;  Xiao, Fengxia; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.8/4.0 | Submit date：2024/05/16
Ancient Genome  Conservation  Dna Mismatch Repair  Evolutionary Origin  Pathogenic Variant  
Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens Journal article
Zhang,Nian, Shan,Wenying, Gao,Liangliang, Kou,Si Hoi, Lu,Chang, Yang,Huilin, Peng,Bo, Tam,Kin Yip, Lee,Leo Tsz On, Zheng,Jun. Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens[J]. International Journal of Antimicrobial Agents, 2023, 62(3), 106888.
Authors:  Zhang,Nian;  Shan,Wenying;  Gao,Liangliang;  Kou,Si Hoi;  Lu,Chang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.9/5.6 | Submit date：2023/08/03
Antibiotic Resistance  Colistin Adjuvant  Drug Repurposing  Eskape  Membrane-disruptive Drug  
TP53 germline pathogenic variants in modern humans were likely originated during recent human history Journal article
Si Hoi Kou, Jiaheng Li, Benjamin Tam,, Huijun Lei, Bojin Zhao, Fengxia Xiao, San Ming Wang. TP53 germline pathogenic variants in modern humans were likely originated during recent human history[J]. NAR Cancer, 2023, 5(3), zcad025.
Authors:  Si Hoi Kou;  Jiaheng Li;  Benjamin Tam,;  Huijun Lei;  Bojin Zhao; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:3.4/4.1 | Submit date：2023/08/03
Evolutionary Origin of MUTYH Germline Pathogenic Variations in Modern Humans Journal article
Xiao,Fengxia, Li,Jiaheng, Lagniton,Philip Naderev Panuringan, Kou,Si Hoi, Lei,Huijun, Tam,Benjamin, Wang,San Ming. Evolutionary Origin of MUTYH Germline Pathogenic Variations in Modern Humans[J]. Biomolecules, 2023, 13(3).
Authors:  Xiao,Fengxia;  Li,Jiaheng;  Lagniton,Philip Naderev Panuringan;  Kou,Si Hoi;  Lei,Huijun; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:4.8/5.4 | Submit date：2023/08/03
Ancient Humans  Archaeological  Evolutionary Origin  Mutyh  Pathogenic Variant  Phylogenic  
Ethnic-specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population Journal article
Qin, Zixin, Li, Jiaheng, Tam, Benjamin, Sinha, Siddharth, Zhao, Bojin, Bhaskaran, Shanmuga Priya, Huang, Teng, Wu, Xiaobing, Chian, Jia Sheng, Guo, Maoni, Kou, Si Hoi, Lei, Huijun, Zhang, Li, Wang, Xiaoyu, Lagniton, Philip Naderev P., Xiao, Fengxia, Jiang, Xinyang, Wang, San Ming. Ethnic-specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population[J]. International Journal of Cancer, 2022, 152(6), 1159-1173.
Authors:  Qin, Zixin;  Li, Jiaheng;  Tam, Benjamin;  Sinha, Siddharth;  Zhao, Bojin; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:5.7/6.0 | Submit date：2023/01/30
Asian  Brca1  Brca2  Cancer  Database  Evolution  Germline Variation  Population  Structure  Variation  
Non-walled spherical Acinetobacter baumannii is an important type of persister upon β-lactam antibiotic treatment Journal article
Jin Zou, Si Hoi Kou, Ruiqiang Xie, Michael S. VanNieuwenhze, Jiuxin Qu, Bo Peng, Jun Zheng. Non-walled spherical Acinetobacter baumannii is an important type of persister upon β-lactam antibiotic treatment[J]. Emerging Microbes and Infections, 2020, 9(1), 1149-1159.
Authors:  Jin Zou;  Si Hoi Kou;  Ruiqiang Xie;  Michael S. VanNieuwenhze;  Jiuxin Qu; et al.
Favorite | TC[WOS]:17 TC[Scopus]:17  IF:8.4/8.3 | Submit date：2021/03/04
Acinetobacter Baumannii  Drug Tolerance  Non-walled Spherical Bacterium  Persisters  Β-lactam Antibiotics