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Patchouli alcohol alleviates metabolic dysfunction-associated steatohepatitis via inhibiting mitochondria-associated endoplasmic reticulum membrane disruption-induced hepatic steatosis and inflammation in rats Journal article
Xie, Xingyu, Liao, Yingyi, Lin, Zixin, Luo, Huijuan, Wei, Guilan, Huang, Ning, Li, Yucui, Chen, Jiannan, Su, Ziren, Yu, Xiuting, Chen, Liping, Liu, Yuhong. Patchouli alcohol alleviates metabolic dysfunction-associated steatohepatitis via inhibiting mitochondria-associated endoplasmic reticulum membrane disruption-induced hepatic steatosis and inflammation in rats[J]. International Immunopharmacology, 2024, 138, 112634.
Authors:  Xie, Xingyu;  Liao, Yingyi;  Lin, Zixin;  Luo, Huijuan;  Wei, Guilan; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.8/5.0 | Submit date：2024/08/05
Inflammation  Metabolic Dysfunction-associated Steatohepatitis  Mitochondria-associated Endoplasmic Reticulum Membrane  Patchouli Alcohol  Steatosis  
Tetrahydroberberine alleviates high-fat diet-induced hyperlipidemia in mice via augmenting lipoprotein assembly-induced clearance of low-density lipoprotein and intermediate-density lipoprotein Journal article
Wei, Guilan, Huang, Ning, Li, Mengyao, Guan, Fengkun, Chen, Liping, Liao, Yingyi, Xie, Xingyu, Li, Yucui, Su, Ziren, Chen, Jiannan, Liu, Yuhong. Tetrahydroberberine alleviates high-fat diet-induced hyperlipidemia in mice via augmenting lipoprotein assembly-induced clearance of low-density lipoprotein and intermediate-density lipoprotein[J]. European Journal of Pharmacology, 2024, 968, 176433.
Authors:  Wei, Guilan;  Huang, Ning;  Li, Mengyao;  Guan, Fengkun;  Chen, Liping; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:4.2/4.3 | Submit date：2024/05/02
Apolipoprotein e  Hyperlipidemia  Lipoprotein Clearance  Low-density Lipoprotein  Tetrahydroberberine  
Curcumin Alleviates High-fat Diet-induced Nonalcoholic Steatohepatitis via Improving Hepatic Endothelial Function with Microbial Biotransformation in Rats Journal article
Wu,Jiazhen, Li,Mengyao, Huang,Ning, Guan,Fengkun, Luo,Huijuan, Chen,Liping, Wei,Guilan, Li,Muxia, Lin,Zhixiu, Su,Ziren, Chen,Jiannan, Liu,Yuhong. Curcumin Alleviates High-fat Diet-induced Nonalcoholic Steatohepatitis via Improving Hepatic Endothelial Function with Microbial Biotransformation in Rats[J]. Journal of Agricultural and Food Chemistry, 2023, 71(27), 10338-10348.
Authors:  Wu,Jiazhen;  Li,Mengyao;  Huang,Ning;  Guan,Fengkun;  Luo,Huijuan; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:5.7/6.0 | Submit date：2023/08/03
Curcumin  Hepatic Endothelial Function  Microbial Biotransformation  Nonalcoholic Steatohepatitis  Tetrahydrocurcumin  
Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes Journal article
Zhao, Jiannan, Li, Yongling, Ma, Jing, Liu, Jingting, Xiao, Ruoxuan, Wang, Linlin, Li, Peng, He, Yinyan, Qian, Feng, Zhang, Ao, Sun, Zhen Liang, Ding, Chunyong. Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes[J]. European Journal of Medicinal Chemistry, 2022, 237, 114338.
Authors:  Zhao, Jiannan;  Li, Yongling;  Ma, Jing;  Liu, Jingting;  Xiao, Ruoxuan; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:6.0/6.1 | Submit date：2022/05/13
Fluorescence Imaging  Inflammasome  Inhibitor  Nlrp3  Sulfonylurea  
The discovery of berberine erythrocyte-hemoglobin self-assembly delivery system: a neglected carrier underlying its pharmacokinetics Journal article
Yu, Qiuxia, Li, Minhua, Chen, Hanbin, Xu, Lieqiang, Cheng, Juanjuan, Lin, Guoshu, Liu, Yuhong, Su, Ziren, Yang, Xiaobo, Li, Yucui, Chen, Jiannan, Xie, Jianhui. The discovery of berberine erythrocyte-hemoglobin self-assembly delivery system: a neglected carrier underlying its pharmacokinetics[J]. DRUG DELIVERY, 2022, 29(1), 856-870.
Authors:  Yu, Qiuxia;  Li, Minhua;  Chen, Hanbin;  Xu, Lieqiang;  Cheng, Juanjuan; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:6.5/6.7 | Submit date：2022/05/17
Berberine  Erythrocyte  Hemoglobin  Pharmacokinetics  Self-assembly System  
β-patchoulene protects against non-alcoholic steatohepatitis via interrupting the vicious circle among oxidative stress, histanoxia and lipid accumulation in rats Journal article
Luo, Huijuan, Xu, Nan, Wu, Jiazhen, Gan, Yuxuan, Chen, Liping, Guan, Fengkun, Li, Mengyao, Li, Yucui, Chen, Jiannan, Su, Ziren, Liu, Yuhong. β-patchoulene protects against non-alcoholic steatohepatitis via interrupting the vicious circle among oxidative stress, histanoxia and lipid accumulation in rats[J]. International Immunopharmacology, 2021, 98, 107915.
Authors:  Luo, Huijuan;  Xu, Nan;  Wu, Jiazhen;  Gan, Yuxuan;  Chen, Liping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:4.8/5.0 | Submit date：2021/12/08
Histanoxia  Non-alcoholic Steatohepatitis  Oxidative Stress  Soluble Cd36  Β-patchoulene  
Oxyberberine, an absorbed metabolite of berberine, possess superior hypoglycemic effect via regulating the PI3K/Akt and Nrf2 signaling pathways Journal article
Dou, Yaoxing, Huang, Ronglei, Li, Qiaoping, Liu, Yuhong, Li, Yucui, Chen, Hanbin, Ai, Gaoxiang, Xie, Jianhui, Zeng, Huifang, Chen, Jiannan, Luo, Chaodan, Su, Ziren. Oxyberberine, an absorbed metabolite of berberine, possess superior hypoglycemic effect via regulating the PI3K/Akt and Nrf2 signaling pathways[J]. Biomedicine and Pharmacotherapy, 2021, 137, 111312.
Authors:  Dou, Yaoxing;  Huang, Ronglei;  Li, Qiaoping;  Liu, Yuhong;  Li, Yucui; et al.
Favorite | TC[WOS]:56 TC[Scopus]:58  IF:6.9/6.8 | Submit date：2021/12/08
Berberine  Diabetes  Metabolite  Oxidative Stress And Inflammation  Oxyberberine  
β-patchoulene improves lipid metabolism to alleviate non-alcoholic fatty liver disease via activating AMPK signaling pathway Journal article
Xu, Nan, Luo, Huijuan, Li, Minyao, Wu, Jiazhen, Wu, Xue, Chen, Liping, Gan, Yuxuan, Guan, Fengkun, Li, Mengyao, Su, Ziren, Chen, Jiannan, Liu, Yuhong. β-patchoulene improves lipid metabolism to alleviate non-alcoholic fatty liver disease via activating AMPK signaling pathway[J]. Biomedicine and Pharmacotherapy, 2021, 134.
Authors:  Xu, Nan;  Luo, Huijuan;  Li, Minyao;  Wu, Jiazhen;  Wu, Xue; et al.
Favorite | TC[WOS]:18 TC[Scopus]:20  IF:6.9/6.8 | Submit date：2021/12/07
Amp-activated Protein Kinase  Hepatic Steatosis  Non-alcoholic Fatty Liver Disease  Pogostemon Cablin  Β-patchoulene  
β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance Journal article
Liu, Yuhong, Wu, Jiazhen, Chen, Liping, Wu, Xue, Gan, Yuxuan, Xu, Nan, Li, Minyao, Luo, Huijuan, Guan, Fengkun, Su, Ziren, Chen, Jiannan, Li, Yucui. β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance[J]. Biochemical Pharmacology, 2020, 182, 114260.
Authors:  Liu, Yuhong;  Wu, Jiazhen;  Chen, Liping;  Wu, Xue;  Gan, Yuxuan; et al.
Favorite | TC[WOS]:22 TC[Scopus]:23  IF:5.3/5.2 | Submit date：2021/12/06
Colitis  Colonic Leakage  Flora Imbalance  Secondary Liver Injury  Β-patchoulene  
Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: Impact on intestinal epithelial barrier, gut microbiota profile and TLR4-MyD88-NF-κB pathway Journal article
Cailan Li, Gaoxiang Ai, Yongfu Wang, Qiang Lu, Chaodan Luo, Lihua Tan, Guosheng Lin, Yuhong Liu, Yucui Li, Huifang Zeng, Jiannan Chen, Zhixiu Lin, Yanfang Xian, Xiaoqi Huang, Jianhui Xie, Ziren Su. Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: Impact on intestinal epithelial barrier, gut microbiota profile and TLR4-MyD88-NF-κB pathway[J]. PHARMACOLOGICAL RESEARCH, 2020, 152.
Authors:  Cailan Li;  Gaoxiang Ai;  Yongfu Wang;  Qiang Lu;  Chaodan Luo; et al.
Favorite | TC[WOS]:178 TC[Scopus]:195  IF:9.1/9.0 | Submit date：2021/12/06
Gut Microflora  Intestinal Epithelial Barrier  Metabolite  Oxyberberine  Tlr4-myd88-nf-κb  Ulcerative Colitis