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Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Ding, Ren Bo, Chen, Ping, Rajendran, Barani Kumar, Lyu, Xueying, Wang, Haitao, Bao, Jiaolin, Zeng, Jianming, Hao, Wenhui, Sun, Heng, Wong, Ada Hang Heng, Valecha, Monica Vishnu, Yang, Eun Ju, Su, Sek Man, Choi, Tak Kan, Liu, Shuiming, Chan, Kin Iong, Yang, Ling Lin, Wu, Jingbo, Miao, Kai, Chen, Qiang, Shim, Joong Sup, Xu, Xiaoling, Deng, Chu Xia. Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics[J]. Nature Communications, 2021, 12(1), 3046.
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao; et al.
Favorite | TC[WOS]:53 TC[Scopus]:53  IF:14.7/16.1 | Submit date：2021/11/30
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Sun, Heng, Zeng, Jianming, Miao, Zhengqiang, Lei, Kuan Cheok, Huang, Chen, Hu, Lingling, Su, Sek Man, Chan, Un In, Miao, Kai, Zhang, Xu, Zhang, Aiping, Guo, Sen, Chen, Si, Meng, Ya, Deng, Min, Hao, Wenhui, Lei, Haipeng, Lin, Ying, Yang, Zhonglin, Tang, Dongjiang, Wong, Koon Ho, Zhang, Xiaohua Douglas, Xu, Xiaoling, Deng, Chu Xia. Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing[J]. Theranostics, 2021, 11(20), 9967 - 9987.
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:12.4/12.0 | Submit date：2021/11/30
Brca1/brca1  Mammary Tumor  Mrc2  Single Cell Rna-seq  Tumor Heterogeneity  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Li,Licen, Bao,Jiaolin, Wang,Haitao, Lei,Josh Haipeng, Peng,Cheng, Zeng,Jianming, Hao,Wenhui, Zhang,Xu, Xu,Xiaoling, Yu,Chundong, Deng,Chu Xia, Chen,Qiang. Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation[J]. Theranostics, 2021, 11(4), 1672-1689.
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:12.4/12.0 | Submit date：2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Chen,Qiang, Lei,Josh Haipeng, Bao,Jiaolin, Wang,Haitao, Hao,Wenhui, Li,Licen, Peng,Cheng, Masuda,Takaaki, Miao,Kai, Xu,Jun, Xu,Xiaoling, Deng,Chu Xia. BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis[J]. Advanced Science, 2020, 7(6), 1903616.
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui; et al.
Favorite | TC[WOS]:51 TC[Scopus]:55  IF:14.3/16.3 | Submit date：2020/09/16
Atm-ampk-drp1  Brca1  Inflammasomes  Mitochondrial Dynamics  Mitophagy  
SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion Journal article
Chen, Qiang, Hao, Wenhui, Xiao, Cuiying, Wang, Ruihong, Xu, Xiaoling, Lu, Huiyan, Chen, Weiping, Deng, Chu-Xia. SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion[J]. CELL REPORTS, 2017, 18(13), 3155-3166.
Authors:  Chen, Qiang;  Hao, Wenhui;  Xiao, Cuiying;  Wang, Ruihong;  Xu, Xiaoling; et al.
Favorite | TC[WOS]:61 TC[Scopus]:63  IF:7.5/8.5 | Submit date：2018/10/30
Cryptotanshinone induces pro-death autophagy through JNK signaling mediated by reactive oxygen species generation in lung cancer cells Journal article
Wenhui Hao, Xuenong Zhang, Wenwen Zhao, Hong Zhu, Zhao-Yang Liu, Jinjian Lu, Xiuping Chen. Cryptotanshinone induces pro-death autophagy through JNK signaling mediated by reactive oxygen species generation in lung cancer cells[J]. Anti-Cancer Agents in Medicinal Chemistry, 2016, 16(5), 593.
Authors:  Wenhui Hao;  Xuenong Zhang;  Wenwen Zhao;  Hong Zhu;  Zhao-Yang Liu; et al.
Favorite | TC[WOS]:23 TC[Scopus]:31 | Submit date：2018/10/30
Cell Death  Cancer  Cryptotanshinone  Ros  Danshen  
Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D Cells Journal article
Hongwei Gao, Wen Sun, Wenwen Zhao, Wenhui Hao, Chung-Hang Leung, Jinjian Lu, Xiuping Chen. Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D Cells[J]. American Journal of Chinese Medicine, 2015, 43(6), 1265-1279.
Authors:  Hongwei Gao;  Wen Sun;  Wenwen Zhao;  Wenhui Hao;  Chung-Hang Leung; et al.
Favorite | TC[WOS]:42 TC[Scopus]:45 | Submit date：2018/11/06
Danshen  Cell Death  Autophagy  Ros  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Jiajie Guo, Wenwen Zhao, Wenhui Hao, Guowen Ren, Jinjian Lu, Xiuping Chen. Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells[J]. Anti-Cancer Agents in Medicinal Chemistry, 2014, 14(8), 1146-1153.
Authors:  Jiajie Guo;  Wenwen Zhao;  Wenhui Hao;  Guowen Ren;  Jinjian Lu; et al.
Favorite | TC[WOS]:33 TC[Scopus]:34 | Submit date：2018/12/28
Cell Death  Cancer  Cucurbitacin b  Dna Damage  Ros  Chinese Medicine  
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner Journal article
Jiajie Guo, Guosheng Wu, Jiaolin Bao, Wenhui Hao, Jinjian Lu, Xiuping Chen. Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner[J]. PLoS ONE, 2014, 9(2).
Authors:  Jiajie Guo;  Guosheng Wu;  Jiaolin Bao;  Wenhui Hao;  Jinjian Lu; et al.
Favorite | TC[WOS]:66 TC[Scopus]:74 | Submit date：2018/10/30
Cell Death  Ros  Cucurbitacin  Chinese Medicine