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A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition Journal article
Song J.-X., Sun Y.-R., Peluso I., Zeng Y., Yu X., Lu J.-H., Xu Z., Wang M.-Z., Liu L.-F., Huang Y.-Y., Chen L.-L., Durairajan S.S.K., Zhang H.-J., Zhou B., Zhang H.-Q., Lu A., Ballabio A., Medina D.L., Guo Z., Li M.. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition[J]. Autophagy, 2016, 12(8), 1372-1389.
Authors:  Song J.-X.;  Sun Y.-R.;  Peluso I.;  Zeng Y.;  Yu X.; et al.
Favorite | TC[WOS]:135 TC[Scopus]:148 | Submit date：2019/01/15
Autophagy  Curcumin Analogs  Lysosomal Biogenesis  Mechanistic Target Of Rapamycin  Transcription Factor Eb  
Tianma Gouteng Yin, a Traditional Chinese Medicine decoction, exerts neuroprotective effects in animal and cellular models of Parkinson's disease Journal article
Liu L.-F., Song J.-X., Lu J.-H., Huang Y.-Y., Zeng Y., Chen L.-L., Durairajan S.S.K., Han Q.-B., Li M.. Tianma Gouteng Yin, a Traditional Chinese Medicine decoction, exerts neuroprotective effects in animal and cellular models of Parkinson's disease[J]. Scientific Reports, 2015, 5.
Authors:  Liu L.-F.;  Song J.-X.;  Lu J.-H.;  Huang Y.-Y.;  Zeng Y.; et al.
Favorite | TC[WOS]:45 TC[Scopus]:55 | Submit date：2019/01/15
Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway Journal article
Chen L.-L., Song J.-X., Lu J.-H., Yuan Z.-W., Liu L.-F., Durairajan S.S.K., Li M.. Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway[J]. Journal of Neuroimmune Pharmacology, 2014, 9(3), 380-387.
Authors:  Chen L.-L.;  Song J.-X.;  Lu J.-H.;  Yuan Z.-W.;  Liu L.-F.; et al.
Favorite | TC[WOS]:78 TC[Scopus]:84 | Submit date：2019/01/15
Alpha-synuclein  Autophagy  Corynoxine  Mtor  Parkinson's Disease  
HMGB1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression :A process modulated by the natural autophagy inducer corynoxine B Journal article
Song J.-X., Lu J.-H., Liu L.-F., Chen L.-L., Durairajan S.S.K., Yue Z., Zhang H.-Q., Li M.. HMGB1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression :A process modulated by the natural autophagy inducer corynoxine B[J]. Autophagy, 2014, 10(1), 144-154.
Authors:  Song J.-X.;  Lu J.-H.;  Liu L.-F.;  Chen L.-L.;  Durairajan S.S.K.; et al.
Favorite | TC[WOS]:127 TC[Scopus]:132 | Submit date：2019/01/15
Autophagy  Corynoxine b  Hmgb1  Parkinson Disease  Snca  
In vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and Traditional Chinese medicine for memory improvement Journal article
Liu L.-F., Durairajan S.S.K., Lu J.-H., Koo I., Li M.. In vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and Traditional Chinese medicine for memory improvement[J]. Journal of Ethnopharmacology, 2012, 141(2), 754-760.
Authors:  Liu L.-F.;  Durairajan S.S.K.;  Lu J.-H.;  Koo I.;  Li M.
Favorite | TC[WOS]:22 TC[Scopus]:27 | Submit date：2019/01/15
Aβ  Alzheimer's Disease  Amyloid Precursor Protein  Ayurvedic Medicine  Traditional Chinese Medicine  
Treatment of idiopathic Parkinson's disease with traditional chinese herbal medicine: A randomized placebo-controlled pilot clinical study Journal article
Li M., Kum W.F., Durairajan S.S.K., Bian Z.X., Man S.C., Lam Y.C., Xie L.X., Lu J.H., Wang Y., Huang X.Z.. Treatment of idiopathic Parkinson's disease with traditional chinese herbal medicine: A randomized placebo-controlled pilot clinical study[J]. Evidence-based Complementary and Alternative Medicine, 2011, 2011.
Authors:  Li M.;  Kum W.F.;  Durairajan S.S.K.;  Bian Z.X.;  Man S.C.; et al.
Favorite | TC[WOS]:35 TC[Scopus]:36 | Submit date：2019/01/15
Baicalein Inhibits Formation of α-Synuclein Oligomers within Living Cells and Prevents Aβ Peptide Fibrillation and Oligomerisation Journal article
Lu J.-H., Ardah M.T., Durairajan S.S.K., Liu L.-F., Xie L.-X., Fong W.-F.D., Hasan M.Y., Huang J.-D., El-Agnaf O.M.A., Li M.. Baicalein Inhibits Formation of α-Synuclein Oligomers within Living Cells and Prevents Aβ Peptide Fibrillation and Oligomerisation[J]. ChemBioChem, 2011, 12(4), 615-624.
Authors:  Lu J.-H.;  Ardah M.T.;  Durairajan S.S.K.;  Liu L.-F.;  Xie L.-X.; et al.
Favorite | TC[WOS]:132 TC[Scopus]:157 | Submit date：2019/01/15
Alpha-synuclein  Amyloid Beta-peptides  Baicalein  Neurological Agents  Oligomerization  
CHRONIC ADMINISTRATION OF BERBERINE INHIBITS AΒ PRODUCTION, PLAQUE FORMATION, GLIOSIS AND COGNITIVE DETERIORATION IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE Conference paper
S.S.K. Durairajan, L.F. Liu, J.H. Lu, I. Koo, K. Maruyama, S.K. Chung, J.D. Huang, M. Li. CHRONIC ADMINISTRATION OF BERBERINE INHIBITS AΒ PRODUCTION, PLAQUE FORMATION, GLIOSIS AND COGNITIVE DETERIORATION IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE[C], 2011.
Authors:  S.S.K. Durairajan;  L.F. Liu;  J.H. Lu;  I. Koo;  K. Maruyama; et al.
Favorite |  | Submit date：2019/02/21
Stimulation of non-amyloidogenic processing of amyloid-β protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-α Journal article
Durairajan S.S.K., Liu L.-F., Lu J.-H., Koo I., Maruyama K., Chung S.K., Huang J.-D., Li M.. Stimulation of non-amyloidogenic processing of amyloid-β protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-α[J]. Journal of Alzheimer's Disease, 2011, 25(2), 245-262.
Authors:  Durairajan S.S.K.;  Liu L.-F.;  Lu J.-H.;  Koo I.;  Maruyama K.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:23 | Submit date：2019/01/15
Adam10  Alzheimer's Disease  Amyloid-β  Chinese Medicine  Cryptotanshinone  Neuroblastoma  Pkc  
The effect of salvianolic acid B combined with laminar shear stress on TNF-α-stimulated adhesion molecule expression in human aortic endothelial cells Journal article
Xie L.X., Durairajan S.S.K., Lu J.H., Liu C.L., Kum W.F., Wang Y., Koo I., Wu W.K., Han D., Lao F., Huang J.-D., Li M.. The effect of salvianolic acid B combined with laminar shear stress on TNF-α-stimulated adhesion molecule expression in human aortic endothelial cells[J]. Clinical Hemorheology and Microcirculation, 2010, 44(4), 245-258.
Authors:  Xie L.X.;  Durairajan S.S.K.;  Lu J.H.;  Liu C.L.;  Kum W.F.; et al.
Favorite | TC[WOS]:16 TC[Scopus]:20 | Submit date：2019/01/15
Adhesion Molecules  Iκbα  Laminar Shear Stress  Nf-κb  Salvianolic Acid b  Tnf-α