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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju Xian, Tong, Benjamin Chun kit, Zhu, Zhou, Su, Cheng Fu, Liu, Jia, Cheung, King Ho, Lu, Jia Hong, Tan, Jie Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min. Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models[J]. Redox Biology, 2022, 51, 102280.
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.; et al.
Favorite | TC[WOS]:47 TC[Scopus]:51  IF:10.7/11.7 | Submit date：2022/05/13
Theranostic  Alzheimer’s Disease  Aβ-targeting  Aβ-aggregate Inhibition  3xtg-ad  5xfad  
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation Journal article
Cai,Cui Zan, Yang,Chuanbin, Zhuang,Xu Xu, Yuan,Ning Ning, Wu,Ming Yue, Tan,Jie Qiong, Song,Ju Xian, Cheung,King Ho, Su,Huanxing, Wang,Yi Tao, Tang,Bei Sha, Behrends,Christian, Durairajan,Siva Sundara Kumar, Yue,Zhenyu, Li,Min, Lu,Jia Hong. NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation[J]. Autophagy, 2020, 17(5), 1112-1130.
Authors:  Cai,Cui Zan;  Yang,Chuanbin;  Zhuang,Xu Xu;  Yuan,Ning Ning;  Wu,Ming Yue; et al.
Favorite | TC[WOS]:30 TC[Scopus]:33  IF:14.6/16.8 | Submit date：2021/03/01
Amaturation  Autophagy  Ccz1-mon1a  Nrbf2  Pi3kc3/ Vps34  Rab7  Trafficking  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Ju-Xian Song, Sandeep Malampati, Yu Zeng, Siva Sundara Kumar Durairajan, Chuan-Bin Yang, Benjamin Chun-Kit Tong, Ashok Iyaswamy, Wen-Bin Shang, Sreenivasmurthy,Sravan Gopalkrishnashetty, Zhou Zhu, King-Ho Cheung, Jia-Hong Lu, Chunzhi Tang, Nenggui Xu, Min Li. A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models[J]. AGING CELL, 2020, 19(2).
Authors:  Ju-Xian Song;  Sandeep Malampati;  Yu Zeng;  Siva Sundara Kumar Durairajan;  Chuan-Bin Yang; et al.
Favorite | TC[WOS]:106 TC[Scopus]:113  IF:8.0/9.7 | Submit date：2021/03/02
Alzheimer's Disease  Beta-amyloid  Curcumin Analog C1  Mapt/tau  Tfeb  
NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models Journal article
Yang, Chuanbin, Cai, Cui-Zan, Song, Ju-Xian, Tan, Jie-Qiong, Durairajan, Siva Sundara Kumar, Iyaswamy, Ashok, Wu, Ming-Yue, Chen, Lei-Lei, Yue, Zhenyu, Li, Min, Lu, Jia-Hong. NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models[J]. AUTOPHAGY, 2017, 13(12), 2028-2040.
Authors:  Yang, Chuanbin;  Cai, Cui-Zan;  Song, Ju-Xian;  Tan, Jie-Qiong;  Durairajan, Siva Sundara Kumar; et al.
Favorite | TC[WOS]:58 TC[Scopus]:60  IF:14.6/16.8 | Submit date：2018/10/30
a Beta  Alzheimer's Disease  App  Autophagy  Class Iii Phosphatidylinositol 3-kinase (Ptdins3k)  Nrbf2  
Efficacy of classic Chinese medicine formula Ditan Decoction for Alzheimer's disease Journal article
CHUA Ka-kit, CHEN Lei-lei, LIU Liang-feng, Durairajan Siva Sundara Kumar, LU Jia-hong, LI Min. Efficacy of classic Chinese medicine formula Ditan Decoction for Alzheimer's disease[J]. Chinese Journal of Integrative Medicine, 2014, 1-5.
Authors:  CHUA Ka-kit;  CHEN Lei-lei;  LIU Liang-feng;  Durairajan Siva Sundara Kumar;  LU Jia-hong; et al.
Favorite | TC[Scopus]:0  IF:2.2/2.3 | Submit date：2019/01/23
Alzheimer's Disease  Chinese Medicine  Ditan Decoction  
Berberine alkaloid as a medicament for prevention and treatment of neural disease Patent
专利类型: 发明专利 Invention, 专利号: US20130237556A1, 申请日期: 2013-03-12,
Authors:  Min LI;  Siva Sundara Kumar DURAIRAJAN;  Liangfeng LIU;  Jiahong LU,
Adobe PDF | Favorite |  | Submit date：2019/01/31
Autophagy Inducing Compounds and the Uses Thereof Patent
专利类型: 发明专利 Invention, 专利号: US20120245190A1, 申请日期: 2012-03-15, 公开日期: 2012-09-27
Authors:  Min Li;  JiaHong LU;  Siva Sundara Kumar DURAIRAJAN;  Liang Feng LIU
Adobe PDF | Favorite |  | Submit date：2019/01/22
Chinese herbal medicinal compound Cory B promotes the clearance of pathogenic protein aggregations associated with Parkinson’s disease via inducing autophagy Journal article
Jia Hong Lu, J. X. Song, Siva Sundara Kumar Durairajan, L. F. Liu, Min Li. Chinese herbal medicinal compound Cory B promotes the clearance of pathogenic protein aggregations associated with Parkinson’s disease via inducing autophagy[J]. ACTA Biophysica Sinica, 2012, 28(7), 21.
Authors:  Jia Hong Lu;  J. X. Song;  Siva Sundara Kumar Durairajan;  L. F. Liu;  Min Li
Favorite |   IF:3.3/3.4 | Submit date：2019/02/01
Systematic Review on the Safety and Efficacy of Herbal Medicine for the Treatment of Vascular Dementia Journal article
Man, Sui Cheung, Chan, Kam Wa, Lu, Jia-Hong, Durairajan, Siva Sundara Kumar, Liu, Liang-Feng, Li, Min. Systematic Review on the Safety and Efficacy of Herbal Medicine for the Treatment of Vascular Dementia[J]. Evidence-Based Complementary and Alternative Medicine, 2012, 2012.
Authors:  Man, Sui Cheung;  Chan, Kam Wa;  Lu, Jia-Hong;  Durairajan, Siva Sundara Kumar;  Liu, Liang-Feng; et al.
Favorite | TC[WOS]:18 TC[Scopus]:24  IF:2.650/3.014 | Submit date：2019/01/21
Efficacy and Safety of Acupuncture for Idiopathic Parkinson’s disease: A Systematic Review Journal article
Lam, Yuen Chi, Kum, Wan Fung, Durairajan, Siva Sundara Kumar, Lu, Jia Hong, Man, Sui Cheung, Xu, Min, Zhang, Xiao Fei, Huang, Xian Zhang, Li, Min. Efficacy and Safety of Acupuncture for Idiopathic Parkinson’s disease: A Systematic Review[J]. Journal of Alternative and Complementary Medicine, 2008, 14(6), 662-670.
Authors:  Lam, Yuen Chi;  Kum, Wan Fung;  Durairajan, Siva Sundara Kumar;  Lu, Jia Hong;  Man, Sui Cheung; et al.
Favorite | TC[WOS]:53 TC[Scopus]:59  IF:2.3/3.7 | Submit date：2019/01/21