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Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches Journal article
Wang, Wei, Deng, Shiwei, Lin, Jinzhong, Ouyang, Defang. Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches[J]. Acta Pharmaceutica Sinica B, 2024, 14(10), 4591-4607.
Authors:  Wang, Wei;  Deng, Shiwei;  Lin, Jinzhong;  Ouyang, Defang
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:14.7/14.1 | Submit date：2024/09/03
Lipid Nanoparticle  Rna  Ionizable Lipid  In Vivo Transportation  Endosomal Escape  Metabolism  Quantum Mechanics  Physiologically-based Pharmacokinetics  
Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights Journal article
López-Estévez, Ana M., Zhang, Y., Medel, María, Arriaga, Iker, Sanjurjo, Lucía, Huck-Iriart, Cristian, Abrescia, Nicola G.A., Vicent, María J., Ouyang, Defang, Torres, Dolores, Alonso, María José. Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights[J]. Nano Research, 2024, 17(10), 9111-9125.
Authors:  López-Estévez, Ana M.;  Zhang, Y.;  Medel, María;  Arriaga, Iker;  Sanjurjo, Lucía; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:9.5/9.0 | Submit date：2024/08/05
Monoclonal Antibody  Nanoparticles  Hyaluronic Acid  Characterization  Particle Size  Computational Modeling  
Predicting Peptide Permeability Across Diverse Barriers: A Systematic Investigation Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Zhu, Yingli, Chen, Fei, Zeng, Wenbin, Ouyang, Defang, Dong, Jie. Predicting Peptide Permeability Across Diverse Barriers: A Systematic Investigation[J]. Molecular Pharmaceutics, 2024, 21(8), 4116-4127.
Authors:  Tan, Xiaorong;  Liu, Qianhui;  Fang, Yanpeng;  Zhu, Yingli;  Chen, Fei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.5/4.6 | Submit date：2024/08/05
Cell Permeability  Drug Delivery  Graph Neural Network  Machine Learning  Peptide  Permeability Prediction  
Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Yang, Sen, Chen, Fei, Wang, Jianmin, Ouyang, Defang, Dong, Jie, Zeng, Wenbin. Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs[J]. Briefings in Bioinformatics, 2024, 25(4), bbae350.
Authors:  Tan, Xiaorong;  Liu, Qianhui;  Fang, Yanpeng;  Yang, Sen;  Chen, Fei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.8/7.9 | Submit date：2024/08/05
Drug Design  Enzymatic Cleavage Features  Half-life  Machine Learning  Peptide Drugs  Transfer Learning  
Self-Assembled Micelles Based on Ginsenoside Rg5 for the Targeted Treatment of PTX-Resistant Tumors Journal article
Gao, Feiyan, Ma, Zhongyi, Luo, Xing, Wang, Yahua, Liu, Xinlong, Tang, Mei, Chen, Junyu, Tu, Liangxing, Ouyang, Defang, Zheng, Ji, Li, Chong. Self-Assembled Micelles Based on Ginsenoside Rg5 for the Targeted Treatment of PTX-Resistant Tumors[J]. Molecular Pharmaceutics, 2024, 21(7), 3502-3512.
Authors:  Gao, Feiyan;  Ma, Zhongyi;  Luo, Xing;  Wang, Yahua;  Liu, Xinlong; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.5/4.6 | Submit date：2024/07/04
Chemotherapy Resistance  Paclitaxel  Paclitaxel-ginsenoside Micelles  Prostate Cancer Treatment  Severe Neurotoxicity  
A Comprehensive Analysis of Biopharmaceutical Products Listed in the FDA’s Purple Book Journal article
Chen, Fuduan, Zhong, Hao, Chan, Ging, Ouyang, Defang. A Comprehensive Analysis of Biopharmaceutical Products Listed in the FDA’s Purple Book[J]. AAPS PharmSciTech, 2024, 25(5), 88.
Authors:  Chen, Fuduan;  Zhong, Hao;  Chan, Ging;  Ouyang, Defang
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.4/3.5 | Submit date：2024/05/16
Biologics  Biopharmaceutical Landscape  Dosage Form  Excipient  Purple Book  
Antibody Recognition of Human Epidermal Growth Factor Receptor-2 (HER2) Juxtamembrane Domain Enhances Anti-Tumor Response of Chimeric Antigen Receptor (CAR)-T Cells Journal article
Zhou, Guangyu, Fu, Shengyu, Zhang, Yunsen, Li, Shuang, Guo, Ziang, Ouyang, Defang, Ying, Tianlei, Lu, Yinying, Zhao, Qi. Antibody Recognition of Human Epidermal Growth Factor Receptor-2 (HER2) Juxtamembrane Domain Enhances Anti-Tumor Response of Chimeric Antigen Receptor (CAR)-T Cells[J]. Antibodies, 2024, 13(2), 45.
Authors:  Zhou, Guangyu;  Fu, Shengyu;  Zhang, Yunsen;  Li, Shuang;  Guo, Ziang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.0/4.7 | Submit date：2024/08/05
Car-t Cell  Her2  Monoclonal Antibody  Trastuzumab  
Perylenedioic Acid-Derived Carbon Dots with Near 100% Quantum Yield in Aqueous Solution for Lasing and Lighting Journal article
Liu, Yupeng, Wang, Bingzhe, Zhang, Yunsen, Guo, Jia, Wu, Xiaoyi, Ouyang, Defang, Chen, Shi, Chen, Yeqing, Wang, Shuangpeng, Xing, Guichuan, Tang, Zikang, Qu, Songnan. Perylenedioic Acid-Derived Carbon Dots with Near 100% Quantum Yield in Aqueous Solution for Lasing and Lighting[J]. Advanced Functional Materials, 2024.
Authors:  Liu, Yupeng;  Wang, Bingzhe;  Zhang, Yunsen;  Guo, Jia;  Wu, Xiaoyi; et al.
Favorite | TC[WOS]:15 TC[Scopus]:11  IF:18.5/19.6 | Submit date：2024/05/16
Aqueous-based Laser  Carbon Dots  Cross-condensation  Near-unity Plqy  White Leds  
Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics Review article
2024
Authors:  Ye, Zhaoyi;  Bao, Ying;  Chen, Zefeng;  Ye, Huiling;  Feng, Zhenzhen; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:20.3/19.9 | Submit date：2024/05/02
Cancer Theranostics  Metal/organic Hybrid Nanomaterials  Organic Ligand  
Organic crystal structure prediction via coupled generative adversarial networks and graph convolutional networks Journal article
Ye, Zhuyifan, Wang, Nannan, Zhou, Jiantao, Ouyang, Defang. Organic crystal structure prediction via coupled generative adversarial networks and graph convolutional networks[J]. Innovation, 2024, 5(2), 100562.
Authors:  Ye, Zhuyifan;  Wang, Nannan;  Zhou, Jiantao;  Ouyang, Defang
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:33.2/31.8 | Submit date：2024/04/02
Monte-carlo  Energy  Polymorph