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Euphorbia helioscopia L. exhibits promising therapeutic effects on hemangioendothelioma and melanoma through angiogenesis inhibition Journal article
Dou, Man, Zhu, Dongliang, Cui, Guozhen, Li, Haixia, Di, Lijun, Wang, Li. Euphorbia helioscopia L. exhibits promising therapeutic effects on hemangioendothelioma and melanoma through angiogenesis inhibition[J]. Phytomedicine, 2024, 129, 155666.
Authors:  Dou, Man;  Zhu, Dongliang;  Cui, Guozhen;  Li, Haixia;  Di, Lijun; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:6.7/6.2 | Submit date：2024/05/16
Angiogenesis  Electron Transport Chain Complex  Euphorbia Helioscopia Extracts  Hemangioendothelioma  Mitochondrial Function  Ros  
J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice Journal article
Pan, Zhijian, Shao, Min, Zhao, Chen, Yang, Xuanjun, Li, Haitao, Cui, Guozhen, Liang, Xiaonan, Yu, Chao Wu, Ye, Qingqing, Gao, Cheng, Di, Lijun, Chern, Ji Wang, Zhou, Hefeng, Lee, Simon Ming Yuen. J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice[J]. European Journal of Pharmaceutical Sciences, 2024, 194, 106696.
Authors:  Pan, Zhijian;  Shao, Min;  Zhao, Chen;  Yang, Xuanjun;  Li, Haitao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.2 | Submit date：2024/04/02
6-ohda  J24335  Mitochondria Dysfunction  Neurotoxicity  Parkinson's Disease  Target Prediction  
Mitochondrial complex I inhibition by homoharringtonine: A novel strategy for suppression of chronic myeloid leukemia Journal article
Han, Han, Zhao, Chen, Liu, Mengchen, Zhu, Hongxuan, Meng, Fancheng, Zhang, Ying, Wang, Guibin, Wang, Li, Di, Lijun, Mingyuen Lee, Simon, Zhang, Qingwen, Cui, Guozhen. Mitochondrial complex I inhibition by homoharringtonine: A novel strategy for suppression of chronic myeloid leukemia[J]. Biochemical Pharmacology, 2023, 218, 115875.
Authors:  Han, Han;  Zhao, Chen;  Liu, Mengchen;  Zhu, Hongxuan;  Meng, Fancheng; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:5.3/5.2 | Submit date：2024/01/02
Chronic Myeloid Leukemia  Homoharringtonine  Mitochondrial Complex i  Oxidative Phosphorylation  Proteomics  T315i Mutation  
Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease Journal article
Bian, Yaqi, Chen, Yan, Wang, Xiufen, Cui, Guozhen, Ung, Carolina Oi Lam, Lu, Jia Hong, Cong, Weihong, Tang, Benqin, Lee, Simon Ming Yuen. Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease[J]. Journal of Advanced Research, 2021, 34, 1-12.
Authors:  Bian, Yaqi;  Chen, Yan;  Wang, Xiufen;  Cui, Guozhen;  Ung, Carolina Oi Lam; et al.
Favorite | TC[WOS]:51 TC[Scopus]:53  IF:11.4/11.0 | Submit date：2022/05/13
Alzheimer's Disease  Amyloid Beta Proteins  Oxidative Stress  Oxyphylla a  Samp8  
Hepatoprotective effect of Qushihuayu formula on non-alcoholic steatohepatitis induced by MCD diet in rat Journal article
Lan, Qingping, Ren, Zhitao, Chen, Yan, Cui, Guozhen, Choi, I. Cheong, Ung, Carolina Oi Lam, Yu, Hon Ho, Lee, Simon Ming Yuen. Hepatoprotective effect of Qushihuayu formula on non-alcoholic steatohepatitis induced by MCD diet in rat[J]. Chinese Medicine, 2021, 16(1).
Authors:  Lan, Qingping;  Ren, Zhitao;  Chen, Yan;  Cui, Guozhen;  Choi, I. Cheong; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:5.3/5.5 | Submit date：2021/12/09
Non-alcoholic Fatty Liver Disease  Non-alcoholic Steatohepatitis  Traditional Chinese Medicine  Qushihuayu  Mapk Pathway  Ppar-γ  P-p65  Fibrosis  Inflammation  Hscs Reprogramming  Methionine-choline Defcient Diet  
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Zhou,Hefeng, Shao,Min, Yang,Xuanjun, Li,Chuwen, Cui,Guozhen, Gao,Cheng, Di,Lijun, Zhong,Hanbing, Wang,Yuqiang, Zhang,Zaijun, Lee,Simon Ming Yuen. Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo[J]. Oxidative Medicine and Cellular Longevity, 2019, 2019.
Authors:  Zhou,Hefeng;  Shao,Min;  Yang,Xuanjun;  Li,Chuwen;  Cui,Guozhen; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:7.310/8.427 | Submit date：2021/03/01
Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
Mu-Yang Huang, Xiao-Ming Jiang, Yu-Lian Xu, Luo-Wei Yuan, Yu-Chi Chen, Guozhen Cui, Run-Yue Huang, Bo Liu, Yitao Wang, Xiuping Chen, Jin-Jian Lu. Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells[J]. FOOD AND CHEMICAL TOXICOLOGY, 2019, 131.
Authors:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen; et al.
Favorite | TC[WOS]:52 TC[Scopus]:50  IF:3.9/4.5 | Submit date：2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat Journal article
Yu Feng, Yan Chen, Binrui Yang, Qingping Lan, Tao Wang, Guozhen Cui, Zhitao Ren, I. Cheong Choi, George Pak-Heng Leung, Fenggen Yan, Dacan Chen, Hon Ho Yu, Simon Ming Yuen Lee. Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat[J]. BIOMED RESEARCH INTERNATIONAL, 2019, 2019.
Authors:  Yu Feng;  Yan Chen;  Binrui Yang;  Qingping Lan;  Tao Wang; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:2.6/3.1 | Submit date：2020/01/16
Design, synthesis and anti-platelet aggregation activity study of ginkgolide-1,2,3-triazole derivatives Journal article
Cui,Jian, Hu,Lean, Shi,Wei, Cui,Guozhen, Zhang,Xumu, Zhang,Qing Wen. Design, synthesis and anti-platelet aggregation activity study of ginkgolide-1,2,3-triazole derivatives[J]. Molecules, 2019, 24(11).
Authors:  Cui,Jian;  Hu,Lean;  Shi,Wei;  Cui,Guozhen;  Zhang,Xumu; et al.
Favorite | TC[WOS]:6 TC[Scopus]:9  IF:4.2/4.6 | Submit date：2021/03/02
Ginkgolide  Inhibitor  Platelet-activating Factor Receptor  
A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells Journal article
Ying Zhang, Hongkuan Deng, Hefeng Zhou, Yucong Lu, Luchen Shan, Simon Ming‐Yuen Lee, Guozhen Cui. A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells[J]. JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 120(4), 5913-5922.
Authors:  Ying Zhang;  Hongkuan Deng;  Hefeng Zhou;  Yucong Lu;  Luchen Shan; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:3.0/3.1 | Submit date：2020/01/16
Antitumor  Biotin-conjugated Adtm Analog (Baa)  Cardioprotection  Cardiotoxicity  Doxorubicin (Dox)