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Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists Journal article
Vergelli, Claudia, Schepetkin, Igor A., Ciciani, Giovanna, Cilibrizzi, Agostino, Crocetti, Letizia, Giovannoni, Maria Paola, Guerrini, Gabriella, Iacovone, Antonella, Kirpotina, Liliya N., Ye, Richard D., Quinn, Mark T.. Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists[J]. DRUG DEVELOPMENT RESEARCH, 2017, 78(1), 49-62.
Authors:  Vergelli, Claudia;  Schepetkin, Igor A.;  Ciciani, Giovanna;  Cilibrizzi, Agostino;  Crocetti, Letizia; et al.
View | Adobe PDF | Favorite | TC[WOS]:8 TC[Scopus]:8  IF:3.5/4.0 | Submit date：2018/10/30
Formyl Peptide Receptor  Agonist  Pyridazin-3(2h)-one  Neutrophil  ca2+flux  
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists Journal article
Vergelli C., Schepetkin I.A., Ciciani G., Cilibrizzi A., Crocetti L., Giovannoni M.P., Guerrini G., Iacovone A., Kirpotina L.N., Khlebnikov A.I., Ye R.D., Quinn M.T.. 2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists[J]. Bioorganic and Medicinal Chemistry, 2016, 24(11), 2530-2543.
Authors:  Vergelli C.;  Schepetkin I.A.;  Ciciani G.;  Cilibrizzi A.;  Crocetti L.; et al.
Favorite | TC[WOS]:21 TC[Scopus]:21 | Submit date：2018/11/07
Agonist  Ca2++ Mobilization  Formyl Peptide Receptor (Fpr)  Neutrophil  Pyridazin-3(2h)-one  
6-Methyl-2,4-disubstituted pyridazin-3(2H)-ones: A novel class of small-molecule agonists for formyl peptide receptors Journal article
Cilibrizzi A., Quinn M.T., Kirpotina L.N., Schepetkin I.A., Holderness J., Ye R.D., Rabiet M.-J., Biancalani C., Cesari N., Graziano A., Vergelli C., Pieretti S., Dal Piaz V., Giovannoni M.P.. 6-Methyl-2,4-disubstituted pyridazin-3(2H)-ones: A novel class of small-molecule agonists for formyl peptide receptors[J]. Journal of Medicinal Chemistry, 2009, 52(16), 5044-5057.
Authors:  Cilibrizzi A.;  Quinn M.T.;  Kirpotina L.N.;  Schepetkin I.A.;  Holderness J.; et al.
Favorite | TC[WOS]:48 TC[Scopus]:47 | Submit date：2018/11/07