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Inhibition of bladder cancer growth with homoharringtonine by inactivating integrin α5/β1-FAK/Src axis: A novel strategy for drug application Journal article
Qiushuang Wu, Pengchen Chen, Junnan Li, Ziqi Lin, Qingwen Zhang, Hang Fai Kwok. Inhibition of bladder cancer growth with homoharringtonine by inactivating integrin α5/β1-FAK/Src axis: A novel strategy for drug application[J]. PHARMACOLOGICAL RESEARCH, 2023, 188, 106654.
Authors:  Qiushuang Wu;  Pengchen Chen;  Junnan Li;  Ziqi Lin;  Qingwen Zhang; et al.
Favorite | TC[WOS]:17 TC[Scopus]:17  IF:9.1/9.0 | Submit date：2023/02/22
Bladder Cancer  Extracellular Matrix  Metastasis  Homoharringtonine  
Tributyltin chloride (TBTCL) induces cell injury via dysregulation of endoplasmic reticulum stress and autophagy in Leydig cells Journal article
Chen, Pengchen, Song, Yali, Tang, Li, Zhong, Wenbin, Zhang, Jing Jing, Cao, Min, Chen, Junhui, Cheng, Guangqing, Li, Huiying, Fan, Tianyun, Kwok, Hang Fai, Wang, Jigang, Yang, Chuanbin, Xiao, Wei. Tributyltin chloride (TBTCL) induces cell injury via dysregulation of endoplasmic reticulum stress and autophagy in Leydig cells[J]. Journal of Hazardous Materials, 2023, 448, 130785.
Authors:  Chen, Pengchen;  Song, Yali;  Tang, Li;  Zhong, Wenbin;  Zhang, Jing Jing; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:12.2/11.9 | Submit date：2023/02/28
Tributyltin Chloride  Leydig Cell  Endoplasmic Reticulum Stress  Autophagy  
A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis Journal article
Li, Junnan, Chen, Pengchen, Wu, Qiushuang, Guo, Libin, Leong, Ka Weng, Chan, Kin Iong, Kwok, Hang Fai. A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis[J]. Cellular and Molecular Life Sciences, 2022, 79(12), 614.
Authors:  Li, Junnan;  Chen, Pengchen;  Wu, Qiushuang;  Guo, Libin;  Leong, Ka Weng; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:6.2/7.7 | Submit date：2023/01/30
Antibody Therapy  Cell Death  Drug Target  Precision Oncology  Small Molecule  
RUNDC3A regulates SNAP25-mediated chemotherapy resistance by binding AKT in gastric neuroendocrine carcinoma (GNEC) Journal article
Pengchen Chen, Wei Wang, Sin Wa Wong, Junnan Li, Qiushaung Wu, Shu-Dong Zhang, Yao Lin, Hang Fai Kwok. RUNDC3A regulates SNAP25-mediated chemotherapy resistance by binding AKT in gastric neuroendocrine carcinoma (GNEC)[J]. Cell Death Discovery, 2022, 8(1), 296.
Authors:  Pengchen Chen;  Wei Wang;  Sin Wa Wong;  Junnan Li;  Qiushaung Wu; et al.
Favorite | TC[WOS]:11 TC[Scopus]:11  IF:6.1/6.0 | Submit date：2022/08/01
Signaling Pathways  Drug-resistance  Grade 3  Transcriptome  Neoplasm  Cancer  Tumors  
Exploration of gastric neuroendocrine carcinoma (GNEC) specific signaling pathways involved in chemoresistance via transcriptome and in vitro analysis Journal article
Xie,Jianwei, Chen,Pengchen, Xie,Hongteng, Sun,Yuqin, Huang,Zhen, Wei,Ran, Miao,Zhengqiang, Wang,Qingshui, Zhang,Shu Dong, Wong,Koon Ho, Lin,Yao, Huang,Changming, Kwok,Hang Fai. Exploration of gastric neuroendocrine carcinoma (GNEC) specific signaling pathways involved in chemoresistance via transcriptome and in vitro analysis[J]. Computational and Structural Biotechnology Journal, 2020, 18, 2610-2620.
Authors:  Xie,Jianwei;  Chen,Pengchen;  Xie,Hongteng;  Sun,Yuqin;  Huang,Zhen; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:4.4/5.0 | Submit date：2021/03/04
Chemoresistance  Gac  Gnec  Neurod1  Transcriptome Analysis  
Signaling networks and the feasibility of computational analysis in gastroenteropancreatic neuroendocrine tumors Journal article
Chen,Pengchen, Wang,Qingshui, Xie,Jianwei, Kwok,Hang Fai. Signaling networks and the feasibility of computational analysis in gastroenteropancreatic neuroendocrine tumors[J]. Seminars in Cancer Biology, 2019, 58, 80-89.
Authors:  Chen,Pengchen;  Wang,Qingshui;  Xie,Jianwei;  Kwok,Hang Fai
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:12.1/13.2 | Submit date：2021/03/04
Neuroendocrine Tumor  Pancreas  Chemotherapy  Signaling Pathway  Gastrointestinal Tract