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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation
Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:
Gong, Xiaoqing
;
Li, Shuli
;
Huang, Junli
;
Tan, Shuoyan
;
Zhang, Qianqian
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
6.0
/
6.1
|
Submit date:2024/10/10
Lrrk2
Virtual Screening
Fingerprint
Pharmacophore
Molecular Docking
Zebrafish
A polyphenol-derived redox-active and conductive nanoparticle-reinforced hydrogel with wet adhesiveness for myocardial infarction repair by simultaneously stimulating anti-inflammation and calcium homeostasis pathways
Journal article
Chen, Peier, Zhang, Wei, Fan, Xianglin, Shi, Xu, Jiang, Yanan, Yan, Liwei, Li, Hekai, Wang, Chunming, Han, Lu, Lu, Xiong, Ou, Caiwen. A polyphenol-derived redox-active and conductive nanoparticle-reinforced hydrogel with wet adhesiveness for myocardial infarction repair by simultaneously stimulating anti-inflammation and calcium homeostasis pathways[J]. Nano Today, 2024, 55, 102157.
Authors:
Chen, Peier
;
Zhang, Wei
;
Fan, Xianglin
;
Shi, Xu
;
Jiang, Yanan
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
12
IF:
13.2
/
14.6
|
Submit date:2024/05/02
Calcium Homeostasis
Conductive Nanoparticle
Immunomodulatory Ability
Myocardial Repair
Wet Adhesiveness
Effects of copy number variations on longevity in late-onset Alzheimer’s disease patients: insights from a causality network analysis
Journal article
Hao, Yanan, Li, Chuhao, Wang, He, Ming, Chen. Effects of copy number variations on longevity in late-onset Alzheimer’s disease patients: insights from a causality network analysis[J]. Frontiers in Aging Neuroscience, 2023, 15, 1241412.
Authors:
Hao, Yanan
;
Li, Chuhao
;
Wang, He
;
Ming, Chen
Favorite
|
TC[WOS]:
0
TC[Scopus]:
1
IF:
4.1
/
4.6
|
Submit date:2024/02/22
Alzheimer’s Disease
Causality Network
Copy Number Variation
Longevity
Plasminogen Activation
Effects of Copy Number Variations on Longevity in Late-Onset Alzheimer’s Disease Patients: Insights from a Causality Network Analysis
Journal article
Hao,Yanan, Li,Chuhao, Wang, He, Ming,Chen. Effects of Copy Number Variations on Longevity in Late-Onset Alzheimer’s Disease Patients: Insights from a Causality Network Analysis[J]. BioRxiv, 2023.
Authors:
Hao,Yanan
;
Li,Chuhao
;
Wang, He
;
Ming,Chen
Favorite
|
|
Submit date:2023/08/23
Cutoff value of IC50 for drug sensitivity in patient-derived tumor organoids in colorectal cancer
Journal article
Tang, Yuting, Wang, Ting, Hu, Yaowen, Ji, Hongli, Yan, Botao, Hu, Xiarong, Zeng, Yunli, Hao, Yifan, Xue, Weisong, Chen, Zexin, Lan, Jianqiang, Wang, Yanan, Deng, Haijun, Deng, Chuxia, Wu, Xiufeng, Yan, Jun. Cutoff value of IC50 for drug sensitivity in patient-derived tumor organoids in colorectal cancer[J]. iScience, 2023, 26(7).
Authors:
Tang, Yuting
;
Wang, Ting
;
Hu, Yaowen
;
Ji, Hongli
;
Yan, Botao
; et al.
Favorite
|
TC[WOS]:
6
TC[Scopus]:
7
IF:
4.6
/
5.0
|
Submit date:2024/01/02
Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology
Journal article
Wang, Qirou, Li, Nannan, Wang, Yajie, Li, Ruilin, Jia, Yanan, Zhou, Jingna, Liu, Junyu, Zhang, Min, Zhuang, Pengwei, He, Chengwei, Chen, Haixia. Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology[J]. Journal of Ethnopharmacology, 2022, 303, 115949.
Authors:
Wang, Qirou
;
Li, Nannan
;
Wang, Yajie
;
Li, Ruilin
;
Jia, Yanan
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
10
IF:
4.8
/
4.8
|
Submit date:2023/04/03
Antidiabetic Activity
Clerodendranthus Spicatus
Network Pharmacology
Orthosiphoic Acid e
Spheroidization of ultrasonic degraded corn silk polysaccharide to enhance bioactivity by the anti-solvent precipitation method
Journal article
Jia, Yanan, Lu, Yangpeng, Wang, Yajie, Zhang, Min, He, Chengwei, Chen, Haixia. Spheroidization of ultrasonic degraded corn silk polysaccharide to enhance bioactivity by the anti-solvent precipitation method[J]. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2022, 102(1), 53-61.
Authors:
Jia, Yanan
;
Lu, Yangpeng
;
Wang, Yajie
;
Zhang, Min
;
He, Chengwei
; et al.
Favorite
|
TC[WOS]:
11
TC[Scopus]:
11
IF:
3.3
/
4.0
|
Submit date:2022/02/21
Corn Silk Polysaccharide
Glut4
Spheroidization
Ultrasonic Degradation
Α-glucosidase
Recent advances in polysaccharides from edible and medicinal Polygonati rhizoma: From bench to market
Review article
2022
Authors:
He, Yanan
;
Chen, Zhejie
;
Nie, Xin
;
Wang, Di
;
Zhang, Qi
; et al.
Favorite
|
TC[WOS]:
46
TC[Scopus]:
48
IF:
7.7
/
7.7
|
Submit date:2022/02/21
Biological Activities
Dietary Supplement
Extraction
Product Development
Structural Characteristics
Synthesis of hydrogels based on nanocellulose from garlic straw and regulating the release of allicin and its cytotoxicity
Journal article
Gao, Xudong, Jia, Yanan, Chen, Zhongqin, Santhanam, Ramesh Kumar, Zhang, Min, He, Chengwei, Chen, Haixia. Synthesis of hydrogels based on nanocellulose from garlic straw and regulating the release of allicin and its cytotoxicity[J]. Food Science and Technology, 2022, 42, e43422.
Authors:
Gao, Xudong
;
Jia, Yanan
;
Chen, Zhongqin
;
Santhanam, Ramesh Kumar
;
Zhang, Min
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
4
IF:
2.602
/
2.968
|
Submit date:2022/08/05
Allicin
Anticancer
Drug Release
Garlic Straw
Hydrogels
Polysaccharides from mulberry (Morus alba L.) leaf prevents obesity by inhibiting pancreatic lipase in high-fat diet induced mice
Journal article
Li, Ruilin, Xue, Zihan, Jia, Yanan, Wang, Yajie, Li, Shuqin, Zhou, Jingna, Liu, Junyu, Zhang, Min, He, Chengwei, Chen, Haixia. Polysaccharides from mulberry (Morus alba L.) leaf prevents obesity by inhibiting pancreatic lipase in high-fat diet induced mice[J]. International Journal of Biological Macromolecules, 2021, 192, 452-460.
Authors:
Li, Ruilin
;
Xue, Zihan
;
Jia, Yanan
;
Wang, Yajie
;
Li, Shuqin
; et al.
Favorite
|
TC[WOS]:
47
TC[Scopus]:
55
IF:
7.7
/
7.7
|
Submit date:2021/12/08
Interaction Mechanism
Mulberry Leaf Polysaccharides
Pancreatic Lipase