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Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β Journal article
Shao-Ru Chen, Zheng-Qing Li, Jun Xu, Mo-Yu Ding, Yaming Shan, Yung-Chi Cheng, Gao-Xiao Zhang, Ye-Wei Sun, Yuqiang Wang, Wang Y(王穎). Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β[J]. ACTA PHARMACOLOGICA SINICA, 2023, 44, 1637-1648.
Authors:  Shao-Ru Chen;  Zheng-Qing Li;  Jun Xu;  Mo-Yu Ding;  Yaming Shan; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.9/7.6 | Submit date：2023/07/06
Celastrol  Heat Shock Protein 90β  Hepatitis c Virus  Inflammatory Response  Rna-dependent Rna Polymerase  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
Chen, Shao-Ru, Li, Feng, Ding, Mo-Yu, Wang, Decai, Zhao, Qi, Wang, Yitao, Zhou, Guo-Chun, Wang, Ying. Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 26(18), 5053-5061.
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi; et al.
View | Adobe PDF | Favorite | TC[WOS]:15 TC[Scopus]:16  IF:3.3/3.1 | Submit date：2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide Journal article
Yan Dai, Shao-Ru Chen, Ling Chai, Jing Zhao, Yitao Wang, Ying Wang. Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide[J]. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2018, 59(sup1), S17-S29.
Authors:  Yan Dai;  Shao-Ru Chen;  Ling Chai;  Jing Zhao;  Yitao Wang; et al.
Favorite | TC[WOS]:207 TC[Scopus]:223  IF:7.3/10.3 | Submit date：2019/11/22
Andrographis Paniculata  Andrographolide  Mechanisms Of Action  Structureactivity-relationship  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
Li, Feng, Li, Xiao-Min, Sheng, Dekuan, Chen, Shao-Ru, Nie, Xin, Liu, Zhuyun, Wang, Decai, Zhao, Qi, Wang, Yitao, Wang, Ying, Zhou, Guo-Chun. Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity[J]. RSC ADVANCES, 2018, 8(17), 9440-9456.
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin; et al.
View | Adobe PDF | Favorite | TC[WOS]:20 TC[Scopus]:21  IF:3.9/3.9 | Submit date：2018/10/30
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
Zhao, Qianqian, Miriyala, Nikhila, Su, Yan, Chen, Weijie, Gao, Xuejiao, Shao, Ling, Yan, Ru, Li, Haifeng, Yao, Xiaojun, Cao, Dongsheng, Wang, Yitao, Ouyang, Defang. Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System[J]. MOLECULAR PHARMACEUTICS, 2018, 15(4), 1664-1673.
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao; et al.
View | Adobe PDF | Favorite | TC[WOS]:46 TC[Scopus]:58  IF:4.5/4.6 | Submit date：2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F Journal article
Chen, Shao-Ru, Dai, Yan, Zhao, Jing, Lin, Ligen, Wang, Yitao, Wang, Ying. A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F[J]. FRONTIERS IN PHARMACOLOGY, 2018, 9.
Authors:  Chen, Shao-Ru;  Dai, Yan;  Zhao, Jing;  Lin, Ligen;  Wang, Yitao; et al.
Favorite | TC[WOS]:249 TC[Scopus]:251  IF:4.4/5.0 | Submit date：2018/10/30
Tripterygium Wilfordii Hook f  Triptolide  Celastrol  Mechanisms Of Action  Structure-activity-relationship  
Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents Journal article
Wang, Ying, Chen, Shao-Ru, Yang, Xiaoming, Lee, Kuo-Hsiung, Cheng, Yung-Chi. Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 26(3), 630-636.
Authors:  Wang, Ying;  Chen, Shao-Ru;  Yang, Xiaoming;  Lee, Kuo-Hsiung;  Cheng, Yung-Chi
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:3.3/3.1 | Submit date：2018/10/30
Non-starch polysaccharide from Chinese yam activated RAW 264.7 macrophages through the Toll-like receptor 4 (TLR4)-NF-κB signaling pathway Journal article
Min Li, Ling-Xiao Chen, Shao-Ru Chen, Yong Deng, Jing Zhao, Ying Wang, Shao-Ping Li. Non-starch polysaccharide from Chinese yam activated RAW 264.7 macrophages through the Toll-like receptor 4 (TLR4)-NF-κB signaling pathway[J]. Journal of Functional Foods, 2017, 37, 491-500.
Authors:  Min Li;  Ling-Xiao Chen;  Shao-Ru Chen;  Yong Deng;  Jing Zhao; et al.
Favorite | TC[WOS]:41 TC[Scopus]:47 | Submit date：2018/12/28
Chinese Yam  Immunogenic Activity  Nf-κb Singling  Non-starch Polysaccharide  Raw 264.7 Macrophages  Toll-like Receptor 4  
Non-starch polysaccharide from Chinese yam activated RAW 264.7 macrophages through the Toll-like receptor 4 (TLR4)-NF-kappa B signaling pathway Journal article
Min Li, Ling-Xiao Chen, Shao-Ru Chen, Yong Deng, Jing Zhao, Ying Wang, Shao-Ping Li. Non-starch polysaccharide from Chinese yam activated RAW 264.7 macrophages through the Toll-like receptor 4 (TLR4)-NF-kappa B signaling pathway[J]. Journal of Functional Foods, 2017, 37, 491-500.
Authors:  Min Li;  Ling-Xiao Chen;  Shao-Ru Chen;  Yong Deng;  Jing Zhao; et al.
Favorite | TC[WOS]:41 TC[Scopus]:47  IF:3.8/4.6 | Submit date：2019/11/22
Non-starch Polysaccharide  Chinese Yam  Raw 264.7 Macrophages  Immunogenic Activity  Nf-jb Singling  Toll-like Receptor 4  
Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-kappa B Signaling Pathway Journal article
Nie, Xin, Chen, Shao-Ru, Wang, Kun, Peng, Yuran, Wang, Yi-Tao, Wang, Decai, Wang, Ying, Zhou, Guo-Chun. Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-kappa B Signaling Pathway[J]. SCIENTIFIC REPORTS, 2017, 7.
Authors:  Nie, Xin;  Chen, Shao-Ru;  Wang, Kun;  Peng, Yuran;  Wang, Yi-Tao; et al.
Favorite | TC[WOS]:31 TC[Scopus]:35  IF:3.8/4.3 | Submit date：2018/10/30