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Brønsted Base-Mediated Aziridination of 2-Alkyl-Substituted-1,3-Dicarbonyl Compounds and 2-Acyl-Substituted-1,4-Dicarbonyl Compounds by Iminoiodanes Journal article
Tejo C., Tirtorahardjo D., Day D.P., Ma D.-L., Leung C.-H., Chan P.W.H.. Brønsted Base-Mediated Aziridination of 2-Alkyl-Substituted-1,3-Dicarbonyl Compounds and 2-Acyl-Substituted-1,4-Dicarbonyl Compounds by Iminoiodanes[J]. Australian Journal of Chemistry, 2017, 70(4), 430-435.
Authors:  Tejo C.;  Tirtorahardjo D.;  Day D.P.;  Ma D.-L.;  Leung C.-H.; et al.
Favorite | TC[WOS]:3 TC[Scopus]:2 | Submit date：2018/11/06
Iminoiodane- and Bronsted base-mediated cross dehydrogenative coupling of cyclic ethers with 1,3-dicarbonyl compounds Journal article
Tejo C., Sim X.R., Lee B.R., Ayers B.J., Leung C.-H., Ma D.-L., Chan P.W.H.. Iminoiodane- and Bronsted base-mediated cross dehydrogenative coupling of cyclic ethers with 1,3-dicarbonyl compounds[J]. Molecules, 2015, 20(7), 13336-13353.
Authors:  Tejo C.;  Sim X.R.;  Lee B.R.;  Ayers B.J.;  Leung C.-H.; et al.
Favorite | TC[WOS]:8 TC[Scopus]:7 | Submit date：2018/11/06
1,3-dicarbonyl Compounds  C-c Bond Formation  Cross Dehydrogenation Coupling  Iminoiodanes  Metal-free Catalysis  
Silver Triflate Catalyzed Cyclopropyl Carbinol Rearrangement for Benzo[b]oxepine and 2H-Chromene Synthesis Journal article
Chan P.W.H., Teo W.T., Koh S.W.Y., Lee B.R., Ayers B.J., Ma D.-L., Leung C.-H.. Silver Triflate Catalyzed Cyclopropyl Carbinol Rearrangement for Benzo[b]oxepine and 2H-Chromene Synthesis[J]. European Journal of Organic Chemistry, 2015, 2015(20), 4447-4456.
Authors:  Chan P.W.H.;  Teo W.T.;  Koh S.W.Y.;  Lee B.R.;  Ayers B.J.; et al.
Favorite | TC[WOS]:17 TC[Scopus]:20 | Submit date：2018/11/06
Homogeneous Catalysis  Oxygen Heterocycles  Rearrangement  Ring Expansion  Silver  
Gold-catalyzed cycloisomerization and diels-alder reaction of 1,4,9-dienyne esters to 3 a,6-methanoisoindole esters with pro-inflammatory cytokine antagonist activity Journal article
Susanti D., Liu L.-J., Rao W., Lin S., Ma D.-L., Leung C.-H., Chan P.W.H.. Gold-catalyzed cycloisomerization and diels-alder reaction of 1,4,9-dienyne esters to 3 a,6-methanoisoindole esters with pro-inflammatory cytokine antagonist activity[J]. Chemistry - A European Journal, 2015, 21(25), 9111-9118.
Authors:  Susanti D.;  Liu L.-J.;  Rao W.;  Lin S.;  Ma D.-L.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:33 | Submit date：2018/11/06
Alkynes  Cycloisomerization  Cytokine Antagonists  Gold  Homogeneous Catalysis  
Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening Journal article
Leung K.-H., Liu L.-J., Lin S., Lu L., Zhong H.-J., Susanti D., Rao W., Wang M., Che W.I., Chan D.S.H., Leung C.-H., Chan P.W.H., Ma D.-L.. Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening[J]. Methods, 2015, 71(C), 38-43.
Authors:  Leung K.-H.;  Liu L.-J.;  Lin S.;  Lu L.;  Zhong H.-J.; et al.
Favorite | TC[WOS]:22 TC[Scopus]:22 | Submit date：2018/11/06
Pharmacophore  Protein-protein Interaction  Stat3  Virtual Screening  
Pharmacophore modeling for the identification of small-molecule inhibitors of TACE Journal article
Liu L.-J., Leung K.-H., Lin S., Chan D.S.-H., Susanti D., Rao W., Chan P.W.H., Ma D.-L., Leung C.-H.. Pharmacophore modeling for the identification of small-molecule inhibitors of TACE[J]. Methods, 2015, 71(C), 92-97.
Authors:  Liu L.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Susanti D.; et al.
Favorite | TC[WOS]:3 TC[Scopus]:2 | Submit date：2018/11/06
Inhibitor  Pharmacophore  Tace  Tumor Necrosis Factor  Virtual Screening  
Ytterbium(III) triflate catalyzed annulation of propargylic 1,4-diols with aryl sulfonamides to give highly substituted pyrrole derivatives Journal article
Zhang X., Teo J.W., Ma D.-L., Leung C.-H., Chan P.W.H.. Ytterbium(III) triflate catalyzed annulation of propargylic 1,4-diols with aryl sulfonamides to give highly substituted pyrrole derivatives[J]. Tetrahedron Letters, 2014, 55(49), 6703-6707.
Authors:  Zhang X.;  Teo J.W.;  Ma D.-L.;  Leung C.-H.;  Chan P.W.H.
Favorite | TC[WOS]:16 TC[Scopus]:16 | Submit date：2018/11/06
Homogeneous Catalysis  Propargylic 1,4-diols  Pyrroles  Tandem Reactions  Ytterbium(Iii) Triflate  
Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols Journal article
Zhang X., Teo W.T., Rao W., Ma D.-L., Leung C.-H., Chan P.W.H.. Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols[J]. Tetrahedron Letters, 2014, 55(29), 3881-3884.
Authors:  Zhang X.;  Teo W.T.;  Rao W.;  Ma D.-L.;  Leung C.-H.; et al.
Favorite | TC[WOS]:23 TC[Scopus]:23 | Submit date：2018/11/06
Brønsted Acid  Friedel-crafts Reaction  Homoallylic Alcohols  Homogeneous Catalysis  Indene Derivatives  
Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme Journal article
Zhong H.-J., Liu L.-J., Chan D.S.-H., Wang H.-M., Chan P.W.H., Ma D.-L., Leung C.-H.. Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme[J]. Biochimie, 2014, 102(1), 211-215.
Authors:  Zhong H.-J.;  Liu L.-J.;  Chan D.S.-H.;  Wang H.-M.;  Chan P.W.H.; et al.
Favorite | TC[WOS]:26 TC[Scopus]:27 | Submit date：2018/11/06
Inhibitor  Nedd8-activating Enzyme  Repurposing  Structure-based  Virtual Screening