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Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model Journal article
Chang, Zhen, Gao, Dan, Liao, Liying, Sun, Junqing, Zhang, Gen, Zhang, Xue, Wang, Feiran, Li, Chunrui, Oladejo, Babayemi Olawale, Li, Shihua, Chai, Yan, Hu, Yongfei, Lu, Xuancheng, Xiao, Haixia, Qi, Jianxun, Chen, Zhihai, Gao, Feng, Wu, Yan. Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model[J]. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(24), e2400163121.
Authors:  Chang, Zhen;  Gao, Dan;  Liao, Liying;  Sun, Junqing;  Zhang, Gen; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:9.4/10.8 | Submit date：2024/07/04
Bispecific Antibody  Bunyavirus  Glycoproteins  Sftsv  Structural Basis  
Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2 Journal article
Rao, Xia, Zhao, Runchu, Tong, Zhou, Guo, Shuxin, Peng, Weiyu, Liu, Kefang, Li, Shihua, Wu, Lili, Tong, Jianyu, Chai, Yan, Han, Pu, Wang, Feiran, Jia, Peng, Li, Zhaohui, Zhao, Xin, Li, Dedong, Zhang, Rong, Zhang, Xue, Zou, Weiwei, Li, Weiwei, Wang, Qihui, Gao, George Fu, Wu, Yan, Dai, Lianpan, Gao, Feng. Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2[J]. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120(52), e2314193120.
Authors:  Rao, Xia;  Zhao, Runchu;  Tong, Zhou;  Guo, Shuxin;  Peng, Weiyu; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:9.4/10.8 | Submit date：2024/01/02
Cryptic Epitope  Neutralizing Antibody  Omicron Ba.4/ba.5/bq.1.1/xbb Subvariant  Rbd-8  Sars-cov-2  
Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine Journal article
Guo Shuxin, Zheng Yuxuan, Gao Zhengrong, Duan Minrun, Liu Sheng, Du Pan, Xu XiaoYu, Xu Kun, Zhao Xin, Chai Yan, Wang Peiyi, Zhao Qi, Gao George F., Dai Lianpan. Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine[J]. Cell Discovery, 2023, 9(1), 79.
Authors:  Guo Shuxin;  Zheng Yuxuan;  Gao Zhengrong;  Duan Minrun;  Liu Sheng; et al.
Adobe PDF | Favorite | TC[WOS]:5 TC[Scopus]:5  IF:13.0/14.8 | Submit date：2023/08/25
Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants Journal article
Zhao,Zhennan, Xie,Yufeng, Bai,Bin, Luo,Chunliang, Zhou,Jingya, Li,Weiwei, Meng,Yumin, Li,Linjie, Li,Dedong, Li,Xiaomei, Li,Xiaoxiong, Wang,Xiaoyun, Sun,Junqing, Xu,Zepeng, Sun,Yeping, Zhang,Wei, Fan,Zheng, Zhao,Xin, Wu,Linhuan, Ma,Juncai, Li,Odel Y., Shang,Guijun, Chai,Yan, Liu,Kefang, Wang,Peiyi, Gao,George F., Qi,Jianxun. Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants[J]. Nature Communications, 2023, 14(1), 4405.
Authors:  Zhao,Zhennan;  Xie,Yufeng;  Bai,Bin;  Luo,Chunliang;  Zhou,Jingya; et al.
Favorite | TC[WOS]:15 TC[Scopus]:16  IF:14.7/16.1 | Submit date：2023/08/03
Nardoguaianone L Isolated from Nardostachys jatamansi Improved the Effect of Gemcitabine Chemotherapy via Regulating AGE Signaling Pathway in SW1990 Cells Journal article
Zheng, Yi Dan, Ma, Li Mei, Lu, Jin Jian, Chai, Tian, Naghavi, Mohammad Reza, Ma, Jun Yi, Sang, Chun Yan, Yang, Jun Li. Nardoguaianone L Isolated from Nardostachys jatamansi Improved the Effect of Gemcitabine Chemotherapy via Regulating AGE Signaling Pathway in SW1990 Cells[J]. Molecules, 2022, 27(20), 6849.
Authors:  Zheng, Yi Dan;  Ma, Li Mei;  Lu, Jin Jian;  Chai, Tian;  Naghavi, Mohammad Reza; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:4.2/4.6 | Submit date：2022/11/07
Age-rage Signaling Pathway  Gemcitabine  Pancreatic Cancer  Proteomic  Sw1990 Cells  
Atezolizumab plus platinum-based chemotherapy as first-line therapy for metastatic urothelial cancer: A cost-effectiveness analysis Journal article
Liu, Xiaoyan, Lang, Yitian, Chai, Qingqing, Lin, Yan, Liao, Yahui, Zhu, Yizhun. Atezolizumab plus platinum-based chemotherapy as first-line therapy for metastatic urothelial cancer: A cost-effectiveness analysis[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Liu, Xiaoyan;  Lang, Yitian;  Chai, Qingqing;  Lin, Yan;  Liao, Yahui; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.4/5.0 | Submit date：2023/01/30
Atezolizumab  Cost-effectiveness  Metastatic Urothelial Cancer  Partitioned Survival Model  The Perspective Of The United States And China  
Targets and Effective Constituents of ZhiziBaipi Decoction for Treating Damp-Heat Jaundice Syndrome Based on Chinmedomics Coupled with UPLC-MS/MS Journal article
Wei, Wen Feng, Sun, Hui, Liu, Shao Bo, Lu, Sheng Wen, Zhang, Ai Hua, Wang, Wan Ying, Chai, Wen Jun, Wu, Fang Fang, Yan, Guang Li, Guan, Yu, Wang, Xi Jun. Targets and Effective Constituents of ZhiziBaipi Decoction for Treating Damp-Heat Jaundice Syndrome Based on Chinmedomics Coupled with UPLC-MS/MS[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Wei, Wen Feng;  Sun, Hui;  Liu, Shao Bo;  Lu, Sheng Wen;  Zhang, Ai Hua; et al.
Favorite | TC[WOS]:8 TC[Scopus]:10  IF:4.4/5.0 | Submit date：2023/01/30
Chinmedomics  Combination Mechanism  Damp-heat Jaundice Syndrome  Metabolic Profile  Uplc-ms/ms  Zhizibaipi Decoction  
PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy Journal article
Lu, Dan, Xu, Zepeng, Zhang, Ding, Jiang, Min, Liu, Kefang, He, Juanhua, Ma, Dongli, Ma, Xiaopeng, Tan, Shuguang, Gao, George F., Chai, Yan. PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy[J]. Frontiers in Immunology, 2022, 13, 826045.
Authors:  Lu, Dan;  Xu, Zepeng;  Zhang, Ding;  Jiang, Min;  Liu, Kefang; et al.
Favorite | TC[WOS]:22 TC[Scopus]:24  IF:5.7/6.8 | Submit date：2022/04/06
Antibody  Cemiplimab  Immune Checkpoint Therapy (Ict)  N58 Glycosylation  Pd-1  
Identification of Linear Peptide Immunogens with Verified Broad-spectrum Immunogenicity from the Conserved Regions within the Hemagglutinin Stem Domain of H1N1 Influenza Virus Journal article
Li, Shuang, Qiao, Yongbo, Xu, Yan, Li, Pengju, Nie, Jiaojiao, Zhao, Qi, Chai, Wen, Shi, Yuhua, Kong, Wei, Shan, Yaming. Identification of Linear Peptide Immunogens with Verified Broad-spectrum Immunogenicity from the Conserved Regions within the Hemagglutinin Stem Domain of H1N1 Influenza Virus[J]. Immunological Investigations, 2022, 51(2), 411-424.
Authors:  Li, Shuang;  Qiao, Yongbo;  Xu, Yan;  Li, Pengju;  Nie, Jiaojiao; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:2.9/2.6 | Submit date：2022/05/17
Broad-spectrum Influenza Vaccines  Ferritin  Hemagglutinin Stem  Influenza a Viruses  Neutralizing Activities  
Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch Journal article
Dai, Lianpan, Xu, Kun, Li, Jinhe, Huang, Qingrui, Song, Jian, Han, Yuxuan, Zheng, Tianyi, Gao, Ping, Lu, Xuancheng, Yang, Huabing, Liu, Kefang, Xia, Qianfeng, Wang, Qihui, Chai, Yan, Qi, Jianxun, Yan, Jinghua, Gao, George F.. Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch[J]. NATURE IMMUNOLOGY, 2021, 22(8), 958-968.
Authors:  Dai, Lianpan;  Xu, Kun;  Li, Jinhe;  Huang, Qingrui;  Song, Jian; et al.
Favorite | TC[WOS]:24 TC[Scopus]:26  IF:27.7/28.3 | Submit date：2021/12/08