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Azoramide prevents MPP+-induced dopaminergic neuronal death via upregulating ER chaperone BiP expression Journal article
Nana Ai, Danni Wang, Shuhui Qu, Chi Teng Vong, Mingzhe Yuan, Huanxing Su, Wei Ge, Cheong-Meng Chong. Azoramide prevents MPP+-induced dopaminergic neuronal death via upregulating ER chaperone BiP expression[J]. Free Radical Biology and Medicine, 2023, 208, 299-308.
Authors:  Nana Ai;  Danni Wang;  Shuhui Qu;  Chi Teng Vong;  Mingzhe Yuan; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:7.1/7.9 | Submit date：2023/08/22
Mitochondrial Dysfunction  Dopaminergic Neurons  Azoramide  Bip  Parkinson's Disease  
Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction Journal article
Qingwen Xiao, Bingling Zhong, Ying Hou, Miaojuan Wang, Baojian Guo, Ligen Lin, Yinning Zhou, Xiuping Chen. Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction[J]. Free Radical Biology and Medicine, 2023, 202, 35-45.
Authors:  Qingwen Xiao;  Bingling Zhong;  Ying Hou;  Miaojuan Wang;  Baojian Guo; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:7.1/7.9 | Submit date：2023/07/20
Isobavachalcone  Mitochondria  Mpt-driven Necrosis  Ros  
Inhibition of thioredoxin reductase by natural anticancer candidate β-lapachone accounts for triggering redox activation-mediated HL-60 cell apoptosis Journal article
Zhang, Junmin, Xu, Qianhe, Ma, Di. Inhibition of thioredoxin reductase by natural anticancer candidate β-lapachone accounts for triggering redox activation-mediated HL-60 cell apoptosis[J]. Free Radical Biology and Medicine, 2022, 180, 244-252.
Authors:  Zhang, Junmin;  Xu, Qianhe;  Ma, Di
Favorite | TC[WOS]:13 TC[Scopus]:13  IF:7.1/7.9 | Submit date：2023/01/30
Apoptosis  Natural Product  Reactive Oxygen Species  Redox  Thioredoxin Reductase  Β-lapachone  
Panax Notoginseng Saponins Attenuates Endothelial Dysfunction In Obese and Diabetic Mice through Inhibition of Endoplasmic Reticulum Stress Conference paper
Cheang, Wai San. Panax Notoginseng Saponins Attenuates Endothelial Dysfunction In Obese and Diabetic Mice through Inhibition of Endoplasmic Reticulum Stress[C]:Elsevier, 2022, S41.
Authors:  Cheang, Wai San
Favorite |  | Submit date：2022/08/11
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy Journal article
Qiu, Wen Qiao, Ai, Wei, Zhu, Feng Dan, Zhang, Yue, Guo, Min Song, Law, Betty Yuen Kwan, Wu, Jian Ming, Wong, Vincent Kam Wai, Tang, Yong, Yu, Lu, Chen, Qi, Yu, Chong Lin, Liu, Jian, Qin, Da Lian, Zhou, Xiao Gang, Wu, An Guo. Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy[J]. Free Radical Biology and Medicine, 2022, 179, 76-94.
Authors:  Qiu, Wen Qiao;  Ai, Wei;  Zhu, Feng Dan;  Zhang, Yue;  Guo, Min Song; et al.
Favorite | TC[WOS]:44 TC[Scopus]:48  IF:7.1/7.9 | Submit date：2023/01/30
Mitophagy  Neurodegenerative Disease  Nlrp3 Inflammasome  Polygala Saponins  Radix Polygalae  Shp-2  
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Yu, Jie, Zhong, Bingling, Zhao, Lin, Hou, Ying, Wang, Xianzhe, Chen, Xiuping. Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1)[J]. FREE RADICAL BIOLOGY AND MEDICINE, 2021, 173, 64-69.
Authors:  Yu, Jie;  Zhong, Bingling;  Zhao, Lin;  Hou, Ying;  Wang, Xianzhe; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:7.1/7.9 | Submit date：2021/12/08
Nec-1  Nec-1s  Nqo1  Ripk1  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Zhong, Bingling, Yu, Jie, Hou, Ying, Ai, Nana, Ge, Wei, Lu, Jin Jian, Chen, Xiuping. A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis[J]. Free Radical Biology and Medicine, 2021, 166, 104-115.
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei; et al.
Favorite | TC[WOS]:13 TC[Scopus]:12  IF:7.1/7.9 | Submit date：2021/09/17
Cell Death  Danshen  Noptosis  Nqo1  
Oxidative stress-mediated AMPK inactivation determines the high susceptibility of LKB1-mutant NSCLC cells to glucose starvation Journal article
Ren, Yi, Chen, Jiaqing, Chen, Peishi, Hao, Qi, Cheong, Leng Kuan, Tang, Mingzhu, Hong, Lian Lian, Hu, Xuan Yu, Celestial T Yap,, Bay, Boon Huat, Ling, Zhi Qiang, Shen, Han Ming. Oxidative stress-mediated AMPK inactivation determines the high susceptibility of LKB1-mutant NSCLC cells to glucose starvation[J]. FREE RADICAL BIOLOGY AND MEDICINE, 2021, 166, 128-139.
Authors:  Ren, Yi;  Chen, Jiaqing;  Chen, Peishi;  Hao, Qi;  Cheong, Leng Kuan; et al.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:7.1/7.9 | Submit date：2021/11/30
Amp-activated Protein Kinase  Glucose Starvation  Liver Kinase B1  Non-small Cell Lung Cancer  Reactive Oxygen Species  
Dual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cells Journal article
Cho,Yik Lam, Tan,Hayden Weng Siong, Saquib,Quaiser, Ren,Yi, Ahmad,Javed, Wahab,Rizwan, He,Weifeng, Bay,Boon Huat, Shen,Han Ming. Dual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cells[J]. Free Radical Biology and Medicine, 2020, 153, 173-186.
Authors:  Cho,Yik Lam;  Tan,Hayden Weng Siong;  Saquib,Quaiser;  Ren,Yi;  Ahmad,Javed; et al.
Favorite | TC[WOS]:27 TC[Scopus]:28  IF:7.1/7.9 | Submit date：2021/03/02
Apoptosis  Autophagy  Jnk  Nio-nps  Oxidative Stress  Ros  
2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Yu, Jie, Zhong, Bingling, Jin, Long, Hou, Ying, Ai, Nana, Ge, Wei, Li, Luoxiang, Liu, Shuqin, Lu, Jin Jian, Chen, Xiuping. 2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1)[J]. Free Radical Biology and Medicine, 2020, 152, 336-347.
Authors:  Yu, Jie;  Zhong, Bingling;  Jin, Long;  Hou, Ying;  Ai, Nana; et al.
Favorite | TC[WOS]:25 TC[Scopus]:27  IF:7.1/7.9 | Submit date：2021/09/17
Mam  Glioblastoma  Programmed Necrosis  Nqo1