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Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo Journal article
Shao, Min, Zhao, Chen, Pan, Zhijian, Yang, Xuanjun, Gao, Cheng, Kam, Gloria Hio Cheng, Zhou, Hefeng, Lee, Simon Ming Yuen. Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo[J]. Chemico-Biological Interactions, 2024, 403, 111224.
Authors:  Shao, Min;  Zhao, Chen;  Pan, Zhijian;  Yang, Xuanjun;  Gao, Cheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.6 | Submit date：2024/10/10
6-ohda  Mitochondria  Neuroprotection  Oxyphylla a  Parkinson's Disease  Target Prediction  
Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models Journal article
Guo, Yizhen, Zhou, Yan, Wu, Puhua, Ran, Maoxin, Xu, Ngai, Shan, Wenying, Sha, Ou, Tam, Kin Yip. Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models[J]. Chemico-Biological Interactions, 2023, 378, 110467.
Authors:  Guo, Yizhen;  Zhou, Yan;  Wu, Puhua;  Ran, Maoxin;  Xu, Ngai; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.7/4.6 | Submit date：2023/07/19
Anticancer Effect  Dichloroacetophenone  Metabolic Alteration  Nsclc  Pdk  
Alcohol triggered bile acid disequilibrium by suppressing BSEP to sustain hepatocellular carcinoma progression Journal article
Chen, Wenbo, Zhang, Qisong, Ding, Ming, Yao, Jingjing, Guo, Yajuan, Yan, Wenxin, Yu, Shaofang, Shen, Qinghong, Huang, Min, Zheng, Yaqiu, Lin, Yuefang, Wang, Ying, Liu, Zhongqiu, Lu, Linlin. Alcohol triggered bile acid disequilibrium by suppressing BSEP to sustain hepatocellular carcinoma progression[J]. Chemico-Biological Interactions, 2022, 356.
Authors:  Chen, Wenbo;  Zhang, Qisong;  Ding, Ming;  Yao, Jingjing;  Guo, Yajuan; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:4.7/4.6 | Submit date：2023/01/30
Bas Homeostasis  Bsep  Epigenetics  Hcc  
Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine Journal article
Hu, Nan, Huang, Yanjuan, Gao, Xuejiao, Li, Sai, Yan, Zhixiang, Wei, Bin, Yan, Ru. Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine[J]. CHEMICO-BIOLOGICAL INTERACTIONS, 2017, 271, 48-58.
Authors:  Hu, Nan;  Huang, Yanjuan;  Gao, Xuejiao;  Li, Sai;  Yan, Zhixiang; et al.
Favorite | TC[WOS]:13 TC[Scopus]:14  IF:4.7/4.6 | Submit date：2018/10/30
Experimental Colitis  Metabolism  Cytochrome P450s  Liver  Kidney  Intestine  Remission  
Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells Journal article
Ma, G, Luo, W, Lu, J., Ma, DL, Leung, C. H., Wang, Y. T., Chen, X. P.. Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells[J]. Chemico-Biological Interactions, 2016, 1-9.
Authors:  Ma, G;  Luo, W;  Lu, J.;  Ma, DL;  Leung, C. H.; et al.
Favorite | TC[WOS]:45 TC[Scopus]:44  IF:4.7/4.6 | Submit date：2022/03/31
Apoptosis  Autophagy  Cancer  Cucurbitacin e  Reactive Oxygen Species  
Cucurbitacin e induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells Journal article
Guixin Ma, Weiwei Luo, Jinjian Lu, Dik-Lung Ma, Chung-Hang Leung, Yitao Wang, Xiuping Chen. Cucurbitacin e induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells[J]. Chemico-Biological Interactions, 2016, 253, 1.
Authors:  Guixin Ma;  Weiwei Luo;  Jinjian Lu;  Dik-Lung Ma;  Chung-Hang Leung; et al.
Favorite | TC[WOS]:45 TC[Scopus]:44  IF:4.7/4.6 | Submit date：2018/10/31
Apoptosis  Autophagy  Cell Death  Cucurbitacin  Ros  Chinese Medicine  
Alterations of testosterone metabolism in microsomes from rats with experimental colitis induced by dextran sulfate sodium Journal article
Huang Y., Hu N., Gao X., Yan Z., Li S., Jing W., Yan R.. Alterations of testosterone metabolism in microsomes from rats with experimental colitis induced by dextran sulfate sodium[J]. Chemico-Biological Interactions, 2015, 232, 38-48.
Authors:  Huang Y.;  Hu N.;  Gao X.;  Yan Z.;  Li S.; et al.
Favorite | TC[WOS]:21 TC[Scopus]:24 | Submit date：2018/12/28
Cytochrome P450s  Dextran Sulfate Sodium -  Experimental Colitis  Metabolism  Testosterone  
Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression Journal article
Wang S., Wang L., Chen M., Wang Y.. Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression[J]. Chemico-Biological Interactions, 2015, 235, 76.
Authors:  Wang S.;  Wang L.;  Chen M.;  Wang Y.
Favorite | TC[WOS]:63 TC[Scopus]:68 | Submit date：2018/10/30
Doxorubicin  Gambogic Acid  Multidrug Resistance  P-glycoprotein  Survivin  
Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases Journal article
Ruan J.-Q., Yan R.. Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases[J]. Chemico-Biological Interactions, 2014, 220, 231-240.
Authors:  Ruan J.-Q.;  Yan R.
Favorite | TC[WOS]:18 TC[Scopus]:22 | Submit date：2018/12/28
Calycosin  Glucuronidation  Metabolism  Regioselectivity  Udp-glucuronosyltransferases  
In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats Journal article
Wu W., Hu N., Zhang Q., Li Y., Li P., Yan R., Wang Y.. In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats[J]. Chemico-Biological Interactions, 2014, 219, 18-27.
Authors:  Wu W.;  Hu N.;  Zhang Q.;  Li Y.;  Li P.; et al.
Favorite | TC[WOS]:53 TC[Scopus]:54  IF:4.7/4.6 | Submit date：2018/10/31
Anthraquinones  Glucuronidation  Regioselectivity  Rhubarb  Ugts