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Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis Journal article
Hu, Xin Yue, Luo, Hui Juan, Wei, Xin, Wang, Yu Zhuo, Ye, Yan Song, Wan, Shi Jie, Zheng, Dan, Zhou, Yu, Xu, Hong Xi, Li, Xing Ren, Lin, Li Gen, Xu, Gang. Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis[J]. Bioorganic Chemistry, 2024, 153, 107864.
Authors:  Hu, Xin Yue;  Luo, Hui Juan;  Wei, Xin;  Wang, Yu Zhuo;  Ye, Yan Song; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.5/4.7 | Submit date:2024/11/05
1l-1β  Anti-inflammatory Activity  Bpap  Garcinia Yunnanensis  Nlrp3  
Dried tangerine peel polysaccharide (DTPP) alleviates hepatic steatosis by suppressing TLR4/MD-2-mediated inflammation and endoplasmic reticulum stress Journal article
Wang, Lingzhi, Li, Wenxi, Li, Yinggang, Chen, Gengrui, Zhao, Lijuan, Li, Wu, Wang, Shengwei, Wang, Chunming, Feng, Yanxian, Zhang, Yibo. Dried tangerine peel polysaccharide (DTPP) alleviates hepatic steatosis by suppressing TLR4/MD-2-mediated inflammation and endoplasmic reticulum stress[J]. Bioorganic Chemistry, 2024, 147, 107369.
Authors:  Wang, Lingzhi;  Li, Wenxi;  Li, Yinggang;  Chen, Gengrui;  Zhao, Lijuan; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.5/4.7 | Submit date:2024/05/16
Nafld  Dried Tangerine Peel Polysaccharide  Inflammation  Endoplasmic Reticulum Stress  Zebrafish  
Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform Journal article
Nao, Sang Cuo, Huang, Le Sheng, Shiu-Hin Chan, Daniel, Wang, Xueliang, Li, Guo Dong, Wu, Jia, Wong, Chun Yuen, Wang, Wanhe, Leung, Chung Hang. Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform[J]. Bioorganic Chemistry, 2024, 144, 107176.
Authors:  Nao, Sang Cuo;  Huang, Le Sheng;  Shiu-Hin Chan, Daniel;  Wang, Xueliang;  Li, Guo Dong; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.5/4.7 | Submit date:2024/04/02
Drug Repurposing  Drug Screening  Iridium(Iii) Complex  Time-resolved Emission  Uracil-dna Glycosylase  
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor Journal article
Sun, Yaoliang, Chen, Zhiwen, Liu, Guobin, Chen, Xiaoai, Shi, Zihan, Feng, Huixu, Yu, Lei, Li, Guodong, Ding, Ke, Huang, He, Zhang, Zhang, Xu, Shilin. Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor[J]. Bioorganic Chemistry, 2023, 143, 107053.
Authors:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.5/4.7 | Submit date:2024/02/22
Cancer  Covalent  Inhibitor  Threonine Tyrosine Kinase (Ttk)  
Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents Journal article
Wang, Yingcai, Nie, Guangli, Wang, Xingshun, Ge, Wei, Zhang, Yandong. Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents[J]. Bioorganic and Medicinal Chemistry Letters, 2023, 96, 129505.
Authors:  Wang, Yingcai;  Nie, Guangli;  Wang, Xingshun;  Ge, Wei;  Zhang, Yandong
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:2.5/2.4 | Submit date:2023/12/04
Cancer  Dhx33  Rna Helicase  Inhibitor High Throughput Screening (Hts)  
Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator Journal article
Lyu, Peng, Li, Shengrong, Han, Ying, Shen, Shengnan, Feng, Zheling, Hao, Piliang, Li, Zhengqiu, Lin, Ligen. Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator[J]. Bioorganic Chemistry, 2023, 133.
Authors:  Lyu, Peng;  Li, Shengrong;  Han, Ying;  Shen, Shengnan;  Feng, Zheling; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.5/4.7 | Submit date:2024/01/10
Activity-based protein profiling  Myotubes  Myricanol  Nampt  Photo-affinity probe  
Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator Other
2023-02-18
Authors:  Lyu, Peng;  Li, Shengrong;  Han, Ying;  Shen, Shengnan;  Feng, Zheling; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4 | Submit date:2023/05/02
Activity-based Protein Profiling  Photo-affinity Probe  Myricanol  Myotubes  Nampt  
Recent development of small-molecular inhibitors against Clostridioides difficile infection Journal article
Chen, Jianwei, Lu, Yaojia, Du, Yujie, Wang, Hong, Wu, Qiang. Recent development of small-molecular inhibitors against Clostridioides difficile infection[J]. Bioorganic Chemistry, 2022, 125.
Authors:  Chen, Jianwei;  Lu, Yaojia;  Du, Yujie;  Wang, Hong;  Wu, Qiang
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:4.5/4.7 | Submit date:2023/01/30
Anti-virulence  Clostridioides Difficile  Inhibitors  Physiological Structures  Small Molecules  
Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors Journal article
Xu, Ting, Meng, Jie Ru, Cheng, Wanqing, Liu, Jia Zheng, Chu, Junyan, Zhang, Qian, Ma, Nannan, Bai, Li Ping, Guo, Yong. Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors[J]. Bioorganic and Medicinal Chemistry, 2022, 67.
Authors:  Xu, Ting;  Meng, Jie Ru;  Cheng, Wanqing;  Liu, Jia Zheng;  Chu, Junyan; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:3.3/3.1 | Submit date:2023/01/30
1,3,4-oxadiazole  Honokiol  Sars-cov-2 Entry Inhibitor  Thioethers  Α-glucosidase Inhibitor  
Caesalpinaxin, a cassane-type diterpenoid with a 21-carbon core skeleton from the seeds of Caesalpinia minax possessing pro-angiogenetic property Journal article
Lou, Ruohan, Xu, Fan, Xu, Yunshao, Chen, Jiali, Feng, Zheling, Gan, Lishe, Lin, Ligen. Caesalpinaxin, a cassane-type diterpenoid with a 21-carbon core skeleton from the seeds of Caesalpinia minax possessing pro-angiogenetic property[J]. Bioorganic Chemistry, 2021, 117, 105426.
Authors:  Lou, Ruohan;  Xu, Fan;  Xu, Yunshao;  Chen, Jiali;  Feng, Zheling; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:4.5/4.7 | Submit date:2021/12/08
Angiogenesis  Caesalpinaxin  Cassalpinia Minax  Ecd  Fabaceae