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Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis
Journal article
Hu, Xin Yue, Luo, Hui Juan, Wei, Xin, Wang, Yu Zhuo, Ye, Yan Song, Wan, Shi Jie, Zheng, Dan, Zhou, Yu, Xu, Hong Xi, Li, Xing Ren, Lin, Li Gen, Xu, Gang. Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis[J]. Bioorganic Chemistry, 2024, 153, 107864.
Authors:
Hu, Xin Yue
;
Luo, Hui Juan
;
Wei, Xin
;
Wang, Yu Zhuo
;
Ye, Yan Song
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
4.5
/
4.7
|
Submit date:2024/11/05
1l-1β
Anti-inflammatory Activity
Bpap
Garcinia Yunnanensis
Nlrp3
Dried tangerine peel polysaccharide (DTPP) alleviates hepatic steatosis by suppressing TLR4/MD-2-mediated inflammation and endoplasmic reticulum stress
Journal article
Wang, Lingzhi, Li, Wenxi, Li, Yinggang, Chen, Gengrui, Zhao, Lijuan, Li, Wu, Wang, Shengwei, Wang, Chunming, Feng, Yanxian, Zhang, Yibo. Dried tangerine peel polysaccharide (DTPP) alleviates hepatic steatosis by suppressing TLR4/MD-2-mediated inflammation and endoplasmic reticulum stress[J]. Bioorganic Chemistry, 2024, 147, 107369.
Authors:
Wang, Lingzhi
;
Li, Wenxi
;
Li, Yinggang
;
Chen, Gengrui
;
Zhao, Lijuan
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
2
IF:
4.5
/
4.7
|
Submit date:2024/05/16
Nafld
Dried Tangerine Peel Polysaccharide
Inflammation
Endoplasmic Reticulum Stress
Zebrafish
Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform
Journal article
Nao, Sang Cuo, Huang, Le Sheng, Shiu-Hin Chan, Daniel, Wang, Xueliang, Li, Guo Dong, Wu, Jia, Wong, Chun Yuen, Wang, Wanhe, Leung, Chung Hang. Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform[J]. Bioorganic Chemistry, 2024, 144, 107176.
Authors:
Nao, Sang Cuo
;
Huang, Le Sheng
;
Shiu-Hin Chan, Daniel
;
Wang, Xueliang
;
Li, Guo Dong
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
2
IF:
4.5
/
4.7
|
Submit date:2024/04/02
Drug Repurposing
Drug Screening
Iridium(Iii) Complex
Time-resolved Emission
Uracil-dna Glycosylase
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
Journal article
Sun, Yaoliang, Chen, Zhiwen, Liu, Guobin, Chen, Xiaoai, Shi, Zihan, Feng, Huixu, Yu, Lei, Li, Guodong, Ding, Ke, Huang, He, Zhang, Zhang, Xu, Shilin. Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor[J]. Bioorganic Chemistry, 2023, 143, 107053.
Authors:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
4.5
/
4.7
|
Submit date:2024/02/22
Cancer
Covalent
Inhibitor
Threonine Tyrosine Kinase (Ttk)
Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents
Journal article
Wang, Yingcai, Nie, Guangli, Wang, Xingshun, Ge, Wei, Zhang, Yandong. Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents[J]. Bioorganic and Medicinal Chemistry Letters, 2023, 96, 129505.
Authors:
Wang, Yingcai
;
Nie, Guangli
;
Wang, Xingshun
;
Ge, Wei
;
Zhang, Yandong
Favorite
|
TC[WOS]:
2
TC[Scopus]:
2
IF:
2.5
/
2.4
|
Submit date:2023/12/04
Cancer
Dhx33
Rna Helicase
Inhibitor High Throughput Screening (Hts)
Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator
Journal article
Lyu, Peng, Li, Shengrong, Han, Ying, Shen, Shengnan, Feng, Zheling, Hao, Piliang, Li, Zhengqiu, Lin, Ligen. Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator[J]. Bioorganic Chemistry, 2023, 133.
Authors:
Lyu, Peng
;
Li, Shengrong
;
Han, Ying
;
Shen, Shengnan
;
Feng, Zheling
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
4.5
/
4.7
|
Submit date:2024/01/10
Activity-based protein profiling
Myotubes
Myricanol
Nampt
Photo-affinity probe
Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator
Other
2023-02-18
Authors:
Lyu, Peng
;
Li, Shengrong
;
Han, Ying
;
Shen, Shengnan
;
Feng, Zheling
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2023/05/02
Activity-based Protein Profiling
Photo-affinity Probe
Myricanol
Myotubes
Nampt
Recent development of small-molecular inhibitors against Clostridioides difficile infection
Journal article
Chen, Jianwei, Lu, Yaojia, Du, Yujie, Wang, Hong, Wu, Qiang. Recent development of small-molecular inhibitors against Clostridioides difficile infection[J]. Bioorganic Chemistry, 2022, 125.
Authors:
Chen, Jianwei
;
Lu, Yaojia
;
Du, Yujie
;
Wang, Hong
;
Wu, Qiang
Favorite
|
TC[WOS]:
4
TC[Scopus]:
5
IF:
4.5
/
4.7
|
Submit date:2023/01/30
Anti-virulence
Clostridioides Difficile
Inhibitors
Physiological Structures
Small Molecules
Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors
Journal article
Xu, Ting, Meng, Jie Ru, Cheng, Wanqing, Liu, Jia Zheng, Chu, Junyan, Zhang, Qian, Ma, Nannan, Bai, Li Ping, Guo, Yong. Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors[J]. Bioorganic and Medicinal Chemistry, 2022, 67.
Authors:
Xu, Ting
;
Meng, Jie Ru
;
Cheng, Wanqing
;
Liu, Jia Zheng
;
Chu, Junyan
; et al.
Favorite
|
TC[WOS]:
10
TC[Scopus]:
10
IF:
3.3
/
3.1
|
Submit date:2023/01/30
1,3,4-oxadiazole
Honokiol
Sars-cov-2 Entry Inhibitor
Thioethers
Α-glucosidase Inhibitor
Caesalpinaxin, a cassane-type diterpenoid with a 21-carbon core skeleton from the seeds of Caesalpinia minax possessing pro-angiogenetic property
Journal article
Lou, Ruohan, Xu, Fan, Xu, Yunshao, Chen, Jiali, Feng, Zheling, Gan, Lishe, Lin, Ligen. Caesalpinaxin, a cassane-type diterpenoid with a 21-carbon core skeleton from the seeds of Caesalpinia minax possessing pro-angiogenetic property[J]. Bioorganic Chemistry, 2021, 117, 105426.
Authors:
Lou, Ruohan
;
Xu, Fan
;
Xu, Yunshao
;
Chen, Jiali
;
Feng, Zheling
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
4.5
/
4.7
|
Submit date:2021/12/08
Angiogenesis
Caesalpinaxin
Cassalpinia Minax
Ecd
Fabaceae