| Residential College | false |
| Status | 已發表Published |
| Clinical research of radiosensitization by CMNa on nasopharyngeal carcinoma of stage IV B | |
| Long B.; Wang Y.; Jiang Y. | |
| 2009-12-14 | |
| Source Publication | Chinese Journal of Cancer Prevention and Treatment
 |
| ISSN | 16735269 |
| Volume | 16Issue:23Pages:1870-1871 |
| Abstract | OBJECTIVE: To evalution the role of CMNa in enhancing radiosensitivity and its safety on the radiotherapy for nasopharyngeal carcinoma of stage IV B. METHODS: A total of 40 patients with nasopharyngeal carcinoma, the lymph of cervix ≥5 cm after 36 Gy irradiation were detected, and 40 patients were randomly divided into CMNa + radiotherapy group (20) and cotrol groups (20). Diagnosis in all cases was confirmed by pathology. The test group were intravenous dripped CMNa 800 mg/m, with 100 mL NS in 30 min, during treatment period by 3D-CRT in 60 min. Patients in control were only treated with 3D-CRT. RESULTS: The treatment outcome was detected after radiotherapy for 70 Gy. The CR rate in the primary site of test group(95%, 19/20) was higher than that of control group(65%, 13/20, P = 0.02). The CR + PR rate in the lymph of cervix of test group(90%, 18/20) was higher than that of group control (55%, 11/20, P = 0.01). CONCLUSIONS: A positive role for enhancing radiosensitivity of nasopharyngeal carcinoma may be indicated, especially grand lymph in cervix. CMNa combined with radiotherapy is well tolerated. Further study on its sensitizing effect is warranted. |
| Keyword | Nasopharyngeal neoplasms/drug therapy Nasopharyngeal neoplasms/radiotherapy |
| URL | View the original |
| Language | 英語English |
| Fulltext Access | |
| Document Type | Journal article |
| Collection | University of Macau |
| Affiliation | Chongqing Cancer Institute |
| Recommended Citation GB/T 7714 | Long B.,Wang Y.,Jiang Y.. Clinical research of radiosensitization by CMNa on nasopharyngeal carcinoma of stage IV B[J]. Chinese Journal of Cancer Prevention and Treatment, 2009, 16(23), 1870-1871. |
| APA | Long B.., Wang Y.., & Jiang Y. (2009). Clinical research of radiosensitization by CMNa on nasopharyngeal carcinoma of stage IV B. Chinese Journal of Cancer Prevention and Treatment, 16(23), 1870-1871. |
| MLA | Long B.,et al."Clinical research of radiosensitization by CMNa on nasopharyngeal carcinoma of stage IV B".Chinese Journal of Cancer Prevention and Treatment 16.23(2009):1870-1871. |
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