Thallium poisoning and emergency care: Research advances

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Status	已發表Published
	Thallium poisoning and emergency care: Research advances
	Wang Y.2; He Y.-Z.1
	2010-04-30
Source Publication	Journal of International Pharmaceutical Research
ISSN	16740440
Volume	37 Issue:2 Pages:118-121
Abstract	As a result of a series of thallium poisoning events, the rare element thallium has attracted wide attention. For nearly a decade, the mechanisms of thallium poisoning and treatment measures have become hot research topics. Preliminary results showed that thallium was absorbed by gastrointestinal tract, respiratory tract and skin, then distributed in the body widely. The thalium concentration in kidneys was the highest, folowed by salivary glands. Thallium ions can replace potassium ion in body and influence the activity of several enzymes. Moreover, thallium can antagonize calcium ions and affect heart function. Clinically, thallium induces peripheral nerve poisoning, gastrointestinal symptoms, mucosal inflammation, hair loss and visual damage. Examination of 24-hour urine thallium concentration is the most accurate way to assess thallium poisoning. If urine thallium concentration is higher than 5 μg/L, it is of diagnostic significance. The clinical treatment measures include reducing the absorption, accelerating elimination and practicing symptomatic treatment. Hemoperfusion has been reported to be effective in eliminating absorbed thallium.
Keyword	Emergency care Neurotoxicity Peripheral neuropathy Thallium poisoning
URL	View the original
Language	英語English
Fulltext Access	View Full-Text via Scopus
Document Type	Journal article
Collection	University of Macau
Affiliation	1.307 Hospital of PIA 2.Capital Medical University China
Recommended Citation GB/T 7714	Wang Y.,He Y.-Z.. Thallium poisoning and emergency care: Research advances[J]. Journal of International Pharmaceutical Research, 2010, 37(2), 118-121.
APA	Wang Y.., & He Y.-Z. (2010). Thallium poisoning and emergency care: Research advances. Journal of International Pharmaceutical Research, 37(2), 118-121.
MLA	Wang Y.,et al."Thallium poisoning and emergency care: Research advances".Journal of International Pharmaceutical Research 37.2(2010):118-121.

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