UM
Patent NumberCN108727484B
Status已授權 Granted
人血清淀粉样蛋白A1功能性短肽及其制备方法和应用
2022-02-01
Application NumberCN201710271556.8
Application Date2017-04-24
Rights Holder上海交通大学 ; 澳门大学
叶德全; 陈明杰; 周慧斌
Date Available2022-02-01
Country中国 China
Abstract本发明公开了一种人血清淀粉样蛋白A1功能性短肽及其制备方法和应用。具体地,本发明提供一种人血清淀粉样蛋白A1多肽片段或其药学上可接受的盐,所述的多肽片段具有以下特征:(i)该多肽片段的序列来源于人血清淀粉样蛋白A1的氨基酸序列;和(ii)该多肽片段为人血清淀粉样蛋白A1(SAA1)全长氨基酸序列(104氨基酸)的第M位到第N位,且长度为42‑67个氨基酸,其中M为9‑14的任一正整数,N为55‑75的任一正整数。本发明的人血清淀粉样蛋白功能性短肽具有抑制致炎细胞因子表达、促进抗炎细胞因子表达的能力,可用于制备治疗炎症疾病的药物。
Language中文Chinese
Open (Notice) NumberCN108727484B
IPC Classification NumberC07K14/47 ; C12N15/12 ; C12N15/81 ; C12N1/19 ; A61K38/17 ; A61P29/00
CPC Classification NumberC07K14/4711 ; A61K38/00 ; A61K38/17 ; A61P29/00 ; C07K14/47 ; C12N15/81
Patent Agent黄丽珍 ; 刘真真
Agency上海一平知识产权代理有限公司 31266
Document TypePatent
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
叶德全,陈明杰,周慧斌. 人血清淀粉样蛋白A1功能性短肽及其制备方法和应用. CN108727484B[P]. 2022-02-01.
APA 叶德全., 陈明杰., & 周慧斌 (2017-04-24). 人血清淀粉样蛋白A1功能性短肽及其制备方法和应用.
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