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Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images
Han, Ruizhi1,2; Liu, Zhulin3; Chen, C. L.Philip2,3,4
2022-05
Source PublicationApplied Soft Computing
ISSN1568-4946
Volume120Pages:108660
Abstract

Alzheimer's disease (AD) has become a severe chronic disease that affects the health of the elderly all over the world. And the number of patients currently suffering continues to rise each year. With the rapid development of medical imaging technology, although researchers have done extensive works on the diagnosis of AD through new computer vision technology, it is still a challenge to realize the diagnosis of AD and Mild Cognitive Impairment (MCI) as precise as possible end-to-end by relying on Magnetic Resonance Imaging (MRI) image resources. In this paper, a new variant model of the Broad Learning System (BLS) for accurate diagnosis of AD and MCI is presented for MRI images. The proposed model is composed of two modules named feature mapping module and feature enhancement module. To adapt to the characteristics of medical images, a new feature mapping module that contains multi groups of feature down-sampling is designed to get the multi-scale features of the images without any additional feature selection. As a result, the proposed model can integrate multi-scale convolution features of the feature mapping module and abstract features of the feature enhancement module end-to-end when learning the AD diagnostic task. At the same time, the proposed model is a lightweight model whose complexity has been significantly simplified. To verify the validity of the proposed model, the ANDI-1 dataset was used in the relevant experiments. After 5-fold cross-validation, the proposed model has achieved the accuracy of 91.83% and 75.52% for the AD diagnostic task and MCI diagnostic task, respectively. The experimental results demonstrate that the proposed model could achieve better performance compared to other methods under the AD and MCI diagnostic tasks.

KeywordAlzheimer's Disease Broad Learning System Convolutional Neural Network Image Classification Magnetic Resonance Imaging
DOI10.1016/j.asoc.2022.108660
URLView the original
Indexed BySSCI
Language英語English
WOS Research AreaComputer Science
WOS SubjectComputer Science, Artificial Intelligence ; Computer Science, Interdisciplinary Applications
WOS IDWOS:000821070000006
PublisherELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
Scopus ID2-s2.0-85126396260
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Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF COMPUTER AND INFORMATION SCIENCE
Corresponding AuthorLiu, Zhulin
Affiliation1.School of Information Science and Engineering, University of Jinan, Shandong, Jinan, 250022, China
2.Faculty of Science and Technology, University of Macau, 99999, China
3.School of Computer Science and Engineering, South China University of Technology, Guangdong, Guangzhou, 510641, China
4.Pazhou Lab, Guangdong, Guangzhou, 510335, China
First Author AffilicationFaculty of Science and Technology
Recommended Citation
GB/T 7714
Han, Ruizhi,Liu, Zhulin,Chen, C. L.Philip. Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images[J]. Applied Soft Computing, 2022, 120, 108660.
APA Han, Ruizhi., Liu, Zhulin., & Chen, C. L.Philip (2022). Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images. Applied Soft Computing, 120, 108660.
MLA Han, Ruizhi,et al."Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images".Applied Soft Computing 120(2022):108660.
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