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Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium
Zhang, H. L.1; Wang, M. L.1; Yi, L. Z.2; Högger, P.3; Arroo, R.4; Bajpai, V. K.5; Prieto, M. A.6; Chen, X. J.1; Simal-Gandara, J.6; Cao, H.6,7
2022-06-01
Source PublicationFood Chemistry
ISSN0308-8146
Volume378Pages:132033
Abstract

Dihydromyricetin has shown many bioactivities in cell level. However, dihydromyricetin was found to be highly instable in cell culture medium DMEM. Here, the underlying degradation mechanism was investigated via UPLC-MS/MS analysis. Dihydromyricetin was mainly converted into its dimers and oxidized products. At lower temperature, dihydromyricetin in DMEM showed higher stability. Vitamin C increased the stability of dihydromyricetin in DMEM probably due to its high antioxidant potential.

KeywordDihydromyricetin Ampelopsin Stability Quinones Dmem Vitamin c
DOI10.1016/j.foodchem.2021.132033
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaChemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS SubjectChemistry, Applied;food Science & Technology;nutrition & Dietetics
WOS IDWOS:000746261300011
PublisherELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
Scopus ID2-s2.0-85122699027
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Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Co-First AuthorZhang, H. L.
Corresponding AuthorChen, X. J.; Simal-Gandara, J.; Cao, H.
Affiliation1.Institute of Chinese Medical Sciences, University of Macau, Macao, China
2.Faculty of Agriculture and Food, Kunming University of Science and Technology, Kunming, 650500, China
3.Institut für Pharmazie und Lebensmittelchemie, Universität Würzburg, Würzburg, 97074, Germany
4.De Montfort University – Leicester School of Pharmacy, The Gateway, Leicester, LE1 9BH, United Kingdom
5.Department of Energy and Materials Engineering, Dongguk University-Seoul, Seoul, 30 Pildong-ro 1-gil, 04620, South Korea
6.Department of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, University of Vigo - Ourense Campus, Ourense, E-32004, Spain
7.College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, 524088, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Zhang, H. L.,Wang, M. L.,Yi, L. Z.,et al. Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium[J]. Food Chemistry, 2022, 378, 132033.
APA Zhang, H. L.., Wang, M. L.., Yi, L. Z.., Högger, P.., Arroo, R.., Bajpai, V. K.., Prieto, M. A.., Chen, X. J.., Simal-Gandara, J.., & Cao, H. (2022). Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium. Food Chemistry, 378, 132033.
MLA Zhang, H. L.,et al."Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium".Food Chemistry 378(2022):132033.
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