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BAF250a protein regulates nucleosome occupancy and histone modifications in priming embryonic stem cell differentiation
Lei I.4; West J.; Yan Z.3; Gao X.1; Fang P.1; Dennis J.H.2; Gnatovskiy L.4; Wang W.3; Kingston R.E.; Wang Z.4
2015-07-31
Source PublicationJournal of Biological Chemistry
ISSN1083351X 00219258
Volume290Issue:31Pages:19343-19352
Abstract

Background: How BAF250a regulates nucleosome configuration in ES cells is not clear. Results: BAF250a regulates nucleosome occupancy and H3K27me3 to control gene expression during ES cell differentiation. Conclusion: BAF250a plays a key role in poised chromatin regulation. Significance: Understanding the mechanisms of chromatin remodeling in poised chromatin regulation provides epigenetic insights into ES cell differentiation.

DOI10.1074/jbc.M115.637389
URLView the original
Language英語English
WOS IDWOS:000358781100045
Scopus ID2-s2.0-84940549895
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Citation statistics
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Massachusetts General Hospital
2.Florida State University
3.National Institutes of Health, Bethesda
4.University of Michigan, Ann Arbor
Recommended Citation
GB/T 7714
Lei I.,West J.,Yan Z.,et al. BAF250a protein regulates nucleosome occupancy and histone modifications in priming embryonic stem cell differentiation[J]. Journal of Biological Chemistry, 2015, 290(31), 19343-19352.
APA Lei I.., West J.., Yan Z.., Gao X.., Fang P.., Dennis J.H.., Gnatovskiy L.., Wang W.., Kingston R.E.., & Wang Z. (2015). BAF250a protein regulates nucleosome occupancy and histone modifications in priming embryonic stem cell differentiation. Journal of Biological Chemistry, 290(31), 19343-19352.
MLA Lei I.,et al."BAF250a protein regulates nucleosome occupancy and histone modifications in priming embryonic stem cell differentiation".Journal of Biological Chemistry 290.31(2015):19343-19352.
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