Residential College | false |
Status | 已發表Published |
Use of voltammetry for in vitro equilibrium and transport studies of ionisable drugs | |
Matěj Velický1; Andrew N.J. Rodgers1; Robert A.W. Dryfe1; Kin Tam2 | |
2014 | |
Source Publication | ADMET & DMPK |
ISSN | 1848-7718 |
Volume | 2Issue:3Pages:143-156 |
Abstract | In this review, we will briefly outline the voltammetric investigations of the transfer of ionisable drugs at the interface between two immiscible electrolyte solutions. The voltammetric techniques enable the determination of some key in vitro properties of ionisable drugs, including partition coefficient, diffusion coefficient and membrane permeability. Some successful applications will be highlighted, together with the background methodologies. |
Keyword | Cyclic Voltammetry Partition Coefficient Diffusion Coefficient Permeability Ities |
DOI | 10.5599/admet.2.3.22 |
Language | 英語English |
WOS ID | WOS:000447332100001 |
Scopus ID | 2-s2.0-84959916162 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | Faculty of Health Sciences |
Corresponding Author | Matěj Velický |
Affiliation | 1.School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, UK 2.Faculty of Health Science, University of Macau, Macau, China |
Recommended Citation GB/T 7714 | Matěj Velický,Andrew N.J. Rodgers,Robert A.W. Dryfe,et al. Use of voltammetry for in vitro equilibrium and transport studies of ionisable drugs[J]. ADMET & DMPK, 2014, 2(3), 143-156. |
APA | Matěj Velický., Andrew N.J. Rodgers., Robert A.W. Dryfe., & Kin Tam (2014). Use of voltammetry for in vitro equilibrium and transport studies of ionisable drugs. ADMET & DMPK, 2(3), 143-156. |
MLA | Matěj Velický,et al."Use of voltammetry for in vitro equilibrium and transport studies of ionisable drugs".ADMET & DMPK 2.3(2014):143-156. |
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