Preparation, characterization and content determination of cubic phase gel containing capsaicin

doi:10.4268/cjcmm20102306

Residential College	false
Status	已發表Published
	Preparation, characterization and content determination of cubic phase gel containing capsaicin
	Peng X.2; Yang Z.3; Chen M.3; Han K.; Xiao Y.3; Wu C.1
	2010-12-01
Source Publication	Zhongguo Zhongyao Zazhi
ISSN	10015302
Volume	35 Issue:23 Pages:3123-3126
Abstract	Objective: To prepare the cubic phase gel containing capsaicin and characterize its properties. Method: The cubic phases gel composed of glycerol monoolein, capsaicin and water was made by self-emulsion technology. The characterization of cubic phase gel was carried out by Cross-Polarizing light microscopy (CPLM) and Small Angle X-Ray Scattering (SAXS). The capsaicin content was determined by HPLC analysis. Result: Under CPLM, cubic phase gel showed dark background. SAXS scattering spectra showed the scattering peaks at 0.1096, 0.1334, 0.1557, 0.1883 Å which was compatible with q :q:q:q = √2: √3: √4: √6. It was well known that the scattering vector ratio was the characteristic of cubic phase and the internal structure was confirmed to be Pn3m (Q). The linear range for capsaicin determination was 3.25 × 10-2.08 × 10 g·L (R = 1). The average recovery was 97.53% with RSD of 2.9% (n = 9). Conclusion: CPLM and SAXS technology are suitable to characterize the cubic phase gel. The determination of the capsaicin content by HPLC is simple and reproducible.
Keyword	Capsaicin Content Determination Cubic Phase Gel Hplc Small Angle X-ray Scattering (Saxs)
DOI	10.4268/cjcmm20102306
URL	View the original
Language	英語English
Scopus ID	2-s2.0-79251511169
Fulltext Access	View Full-Text via DOI View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	University of Macau
Affiliation	1.Gannan Medical College 2.Guangdong Medical University 3.Sun Yat-Sen University
Recommended Citation GB/T 7714	Peng X.,Yang Z.,Chen M.,et al. Preparation, characterization and content determination of cubic phase gel containing capsaicin[J]. Zhongguo Zhongyao Zazhi, 2010, 35(23), 3123-3126.
APA	Peng X.., Yang Z.., Chen M.., Han K.., Xiao Y.., & Wu C. (2010). Preparation, characterization and content determination of cubic phase gel containing capsaicin. Zhongguo Zhongyao Zazhi, 35(23), 3123-3126.
MLA	Peng X.,et al."Preparation, characterization and content determination of cubic phase gel containing capsaicin".Zhongguo Zhongyao Zazhi 35.23(2010):3123-3126.

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