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Fan-shaped complete block on helical tomotherapy for esophageal cancer: A phantom study
Chang C.-H.1,2; Mok G.S.P.3; Shueng P.-W.2; Yeh H.-P.2; Shiau A.-C.4; Tien H.-J.2; Lin C.-T.2; Wu T.-H.1
2015
Source PublicationBioMed Research International
ISSN23146141 23146133
Volume2015
Abstract

Radiation pneumonitis (RP) is a common complication for radiotherapy of esophageal cancer and is associated with the low dose irradiated lung volume. This study aims to reduce the mean lung dose (MLD) and the relative lung volume at 20 Gy (V 20) and at low dose region using various designs of the fan-shaped complete block (FSCB) in helical tomotherapy. Hypothetical esophageal tumor was delineated on an anthropomorphic phantom. The FSCB was defined as the fan-shaped radiation restricted area located in both lungs. Seven treatment plans were performed with nonblock design and FSCB with different fan angles, that is, from 90° to 140°, with increment of 10°. The homogeneous index, conformation number, MLD, and the relative lung volume receiving more than 5, 10, 15, and 20 Gy (V 5, V 10, V 15, and V 20) were determined for each treatment scheme. There was a substantial reduction in the MLD, V 5, V 10, V 15, and V 20 when using different types of FSCB as compared to the nonblock design. The reduction of V 20, V 15, V 10, and V 5 was 6.3%-8.6%, 16%-23%, 42%-57%, and 42%-66% for FSCB 90°-140°, respectively. The use of FSCB in helical tomotherapy is a promising method to reduce the MLD, V 20, and relative lung volume in low dose region, especially in V 5 and V 10 for esophageal cancer.

DOI10.1155/2015/959504
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaBiotechnology & Applied Microbiology ; Research & Experimental Medicine
WOS SubjectBiotechnology & Applied Microbiology ; Medicine, Research & Experimental
WOS IDWOS:000350244400001
Scopus ID2-s2.0-84924104478
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Citation statistics
Document TypeJournal article
CollectionFaculty of Health Sciences
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Affiliation1.Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei 112, Taiwan
2.Division of Radiation Oncology, Department of Radiology, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan
3.Biomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau
4.Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei 112, Taiwan
Recommended Citation
GB/T 7714
Chang C.-H.,Mok G.S.P.,Shueng P.-W.,et al. Fan-shaped complete block on helical tomotherapy for esophageal cancer: A phantom study[J]. BioMed Research International, 2015, 2015.
APA Chang C.-H.., Mok G.S.P.., Shueng P.-W.., Yeh H.-P.., Shiau A.-C.., Tien H.-J.., Lin C.-T.., & Wu T.-H. (2015). Fan-shaped complete block on helical tomotherapy for esophageal cancer: A phantom study. BioMed Research International, 2015.
MLA Chang C.-H.,et al."Fan-shaped complete block on helical tomotherapy for esophageal cancer: A phantom study".BioMed Research International 2015(2015).
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