Residential College | false |
Status | 已發表Published |
Hepatocyte co-culture in alginate hydrogel for anti-cancer drug analysis | |
Chin L.K.; Luo K.Q.; Liu A.Q. | |
2011-12-01 | |
Conference Name | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
Source Publication | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
Volume | 3 |
Pages | 1499-1501 |
Conference Date | October 2-6, 2011 |
Conference Place | Seattle, Washington, USA. |
Country | USA |
Abstract | This paper presents the formation of double-layer cellular tumor spheroid for the co-culture of hepatocyte (HepG2 cancer liver cell and LO2 normal liver cell) using alginate hydrogel. With the microfluidic chip, double-layer cellular tumor spheroid can be formed by the hydrogel droplet to mimic the in vivo environment in which the cancer cell is surrounded by normal cell. A microchip with concentration gradient generation and tumor spheroid trapping site is designed for anti-cancer drug analysis. |
Keyword | Co-culture Drug Analysis Hepatocyte Hydrogel |
URL | View the original |
Language | 英語English |
Fulltext Access | |
Document Type | Conference paper |
Collection | Faculty of Health Sciences |
Corresponding Author | Liu A.Q. |
Affiliation | Nanyang Technological University |
Recommended Citation GB/T 7714 | Chin L.K.,Luo K.Q.,Liu A.Q.. Hepatocyte co-culture in alginate hydrogel for anti-cancer drug analysis[C], 2011, 1499-1501. |
APA | Chin L.K.., Luo K.Q.., & Liu A.Q. (2011). Hepatocyte co-culture in alginate hydrogel for anti-cancer drug analysis. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, 3, 1499-1501. |
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