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An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine
Shengke Li1; Nan Jiang1; Wenxuan Zhao1; Yuan-Fu Ding1; Ying Zheng1; Lian-Hui Wang2; Jun Zheng1; Ruibing Wang1
2017
Source PublicationChemical Communications
ISSN1364548X 13597345
Volume53Issue:43Pages:5870-5873
Abstract

We report an unprecedented, eco-friendly, in situ activatable model antibiotic, phenylalanyl-polyethylenimine (PhePEI), to potentially diminish antibiotic pollution of the environment and associated antibiotic resistance. The inactive PhePEI can be reversibly activated upon supramolecular crosslinking by cucurbit[8]uril, conferring potent antibacterial activity.

DOI10.1039/c7cc02466e
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000402296200019
Scopus ID2-s2.0-85021774256
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Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF PHARMACEUTICAL SCIENCES
Faculty of Health Sciences
THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Affiliation1.University of Macau
2.Nanjing University of Post and TeleCommunications
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Shengke Li,Nan Jiang,Wenxuan Zhao,et al. An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine[J]. Chemical Communications, 2017, 53(43), 5870-5873.
APA Shengke Li., Nan Jiang., Wenxuan Zhao., Yuan-Fu Ding., Ying Zheng., Lian-Hui Wang., Jun Zheng., & Ruibing Wang (2017). An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine. Chemical Communications, 53(43), 5870-5873.
MLA Shengke Li,et al."An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine".Chemical Communications 53.43(2017):5870-5873.
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