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Recent advances in total syntheses of natural products containing the benzocycloheptane motif
Jian-Hong Fan1,2; Ya-Jian Hu1,2; Li-Xuan Li2; Jing-Jing Wang2; Shao-Ping Li1; Jing Zhao1; Chuang-Chuang Li2
Source PublicationNATURAL PRODUCT REPORTS
ISSN0265-0568
2021-03-02
Abstract

Covering: 2010 to 2020 Benzocycloheptane is a fundamental and unique structural motif found in pharmaceuticals and natural products. The total syntheses of natural products bearing the benzocycloheptane subunit are challenging and there are only a few efficient approaches to access benzocycloheptane. Thus, new methods and innovative strategies for preparing such natural products need to be developed. In this review, recent progress in the total syntheses of natural products bearing the benzocycloheptane motif is presented, and key transformations for the construction of benzocycloheptane are highlighted. This review provides a useful guide for those engaged in the syntheses of natural products containing the benzocycloheptane motif.

Language英語English
DOI10.1039/d1np00003a
URLView the original
Volume38
Issue10
Pages1821-1851
WOS IDWOS:000709006100001
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Medicinal ; Chemistry, Organic
WOS Research AreaBiochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry
Indexed BySCIE
Scopus ID2-s2.0-85112524945
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Citation statistics
Document TypeReview article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorJing Zhao; Chuang-Chuang Li
Affiliation1.Institute of Chinese Medical Sciences, University of Macau, Macau, China
2.Shenzhen Grubbs Institute, Department of Chemistry, Guangdong Provincial Key Laboratory of Catalysis, Southern University of Science and Technology, Shenzhen, 518055, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Jian-Hong Fan,Ya-Jian Hu,Li-Xuan Li,et al. Recent advances in total syntheses of natural products containing the benzocycloheptane motif[J]. NATURAL PRODUCT REPORTS, 2021, 38(10), 1821-1851.
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