The COVID-19 pandemic has challenged higher education worldwide. From face-to-face sessions between teachers and students, teaching and learning have to be done online to allow students to continue learning while preventing the spread of this infectious disease. Faced with a wide range of electronic learning systems (ELS) to choose from, this study examined the factors that could affect the students’ intent to re-use the ELS. There were 135 college students in a private university in Manila, Philippines, and 177 college students from a public university in Macau, China, who were surveyed to find out the factors that would influence their intent to re-use ELS. Using structural equation modeling (SMART-PLS), this study showed that there was a significant relationship between perceived ease of use (PE) and perceived usefulness (PU), which were the constructs of the technology acceptance model (TAM). This implies that those who find the ELS easy to use will also find it useful. This study also extended TAM to include intrinsic motivation (IM) and extrinsic motivation (EM) as moderating variables between satisfaction (ST) and intent to re-use the ELS (INT). The result showed that IM and EM did not moderate the relationship between ST and INT. This suggests that Chinese and Filipino students are not motivated to use the ELS. This may be because there is a need to make the ELS enjoyable and engaging. Perceived convenience (PC) was significant to PE and PU. This shows that those who find the ELS convenient find it easy to use and useful. The overall results showed that user training (UT) was significant to PE and PU. This implies that training can stress the usefulness and ease of adopting the ELS. Satisfaction (ST) was significant to INT. The results validate existing literature that those who find the technology easy to use and those who are satisfied with the learning systems are likely to re-use it. This study is one of the few studies in the Philippines that examined the factors that affected students’ re-use of the ELS. It has significant implications for educational institutions in terms of designing an ELS that would encourage students to re-use it, especially during this time when educational institutions have developed courses to be taught in an online environment even if there are vaccines for COVID-19.