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Dairy-Derived and Egg White Proteins in Enhancing Immune System Against COVID-19
Batiha, Gaber El Saber1; Alqarni, Mohammed2; Awad, Dina A.B.3; Algammal, Abdelazeem M.4; Nyamota, Richard5; Wahed, Mir I.I.6; Shah, Muhammad Ajmal7; Amin, Mohammad N.8,9; Adetuyi, Babatunde O.10; Hetta, Helal F.11; Cruz-Martins, Natália12,13,14; Koirala, Niranjan15,16; Ghosh, Arabinda17; Echeverría, Javier18; Pagnossa, Jorge Pamplona19; Sabatier, Jean Marc20
Source PublicationFrontiers in Nutrition
ISSN2296-861X
2021-07-12
Abstract

Coronavirus disease (COVID-19) is a global health challenge, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) triggers a plethora of respiratory disturbances and even multiple organs failure that can be fatal. Nutritional intervention is one of the key components toward to a proper management of COVID-19 patients, especially in those requiring medication, and should thus be considered the first-line treatment. Immuno-modulation and -stimulation are currently being explored in COVID-19 management and are gaining interest by food and pharmaceutical industries. Various dietary combinations, bioactive components, nutrients and fortified foods have been reported to modulate inflammation during disease progression. Dietary combinations of dairy-derived products and eggs are gaining an increasing attention given the huge immunomodulatory and anti-inflammatory properties attributed to some of their chemical constituents. Eggs are complex dietary components containing many essential nutrients and bioactive compounds as well as a high-quality proteins. Similarly, yogurts can replenish beneficial bacteria and contains macronutrients capable of stimulating immunity by enhancing cell immunity, reducing oxidative stress, neutralizing inflammation and regulating the intestinal barriers and gut microbiome. Thus, this review highlights the impact of nutritional intervention on COVID-19 management, focusing on the immunomodulatory and inflammatory effects of immune-enhancing nutrients.

KeywordCoronavirus Disease 2019 Immunomodulation Nutrients Nutritional Therapy Sars-cov-2
Language英語English
DOI10.3389/fnut.2021.629440
URLView the original
Volume8
Pages629440
WOS IDWOS:000677473900001
WOS SubjectNutrition & Dietetics
WOS Research AreaNutrition & Dietetics
Indexed BySCIE
Scopus ID2-s2.0-85111305813
Fulltext Access
Citation statistics
Document TypeReview article
CollectionFaculty of Science and Technology
Corresponding AuthorBatiha, Gaber El Saber; Cruz-Martins, Natália
Affiliation1.Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt
2.Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, Saudi Arabia
3.Department of Food Hygiene, Faculty of Veterinary Medicine, Benha University, Benha, Egypt
4.Department of Bacteriology, Immunology, and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt
5.Department of Biochemistry and Molecular Biology, Faculty of Science, Egerton University, Njoro, Kenya
6.Department of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh
7.Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan
8.Department of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, Bangladesh
9.Pratyasha Health Biomedical Research Center, Dhaka, Bangladesh
10.Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Nigeria
11.Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Asyut, Egypt
12.Faculty of Medicine, University of Porto, Porto, Portugal
13.Institute for Research and Innovation in Health (i3S), University of Porto, Porto, Portugal
14.Laboratory of Neuropsychophysiology, Faculty of Psychology and Education Sciences, University of Porto, Porto, Portugal
15.Department of Natural Products Research, Dr. Koirala Research Institute for Biotechnology and Biodiversity, Kathmandu, Nepal
16.Laboratory of Biotechnology, Faculty of Science and Technology, University of Macau, Taipa, Macao
17.Microbiology Division, Department of Botany, Gauhati University, Guwahati, India
18.Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile
19.Biological Sciences Department, Federal University of Lavras (UFLA), Lavras, Brazil
20.Université Aix-Marseille, Institut de Neuro-Physiopathologie (INP), UMR 7051, Faculté de Pharmacie, Marseille, France
Recommended Citation
GB/T 7714
Batiha, Gaber El Saber,Alqarni, Mohammed,Awad, Dina A.B.,et al. Dairy-Derived and Egg White Proteins in Enhancing Immune System Against COVID-19[J]. Frontiers in Nutrition, 2021, 8, 629440.
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