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A thermal-insensitive all-electronic modular μnmr relaxometer with a 2D digital microfluidic chip for sample management
Lei, Ka Meng; Mak, Pui In; Law, Man Kay; Martins, Rui P.
2015-10
Conference NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Source PublicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Pages302-304
Conference Date25 October 2015 through 29 October 2015
Conference PlaceGyeongju
Abstract

Presented is an electronic-automated micro-Nuclear Magnetic Resonance (μNMR) relaxometer with multi-sample droplet management capability for Point-of-Care diagnostics. Constraints of sample handling inside the cramped magnet are overcome by integration of microfluidic and microelectronic technologies. The two-dimensional digital microfluidic (DMF) device with sample location detecting capability enables automatic sample manipulation. Additionally, a calibrator ensures precise proton excitation against ambient temperature (18-30°C). Experiments have corroborated auto-handling and identification of two targets within 2.2 minutes, indicating it as a promising tool for Point-of-Care application.

KeywordBiosensor Digital Microfluidic Nuclear Magnetic Resonance
URLView the original
Language英語English
Scopus ID2-s2.0-84983266267
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Document TypeConference paper
CollectionFaculty of Science and Technology
THE STATE KEY LABORATORY OF ANALOG AND MIXED-SIGNAL VLSI (UNIVERSITY OF MACAU)
INSTITUTE OF MICROELECTRONICS
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Corresponding AuthorMak, Pui In
AffiliationState-Key Laboratory of Analog and Mixed-Signal VLSI, University of Macau, Macao
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Lei, Ka Meng,Mak, Pui In,Law, Man Kay,et al. A thermal-insensitive all-electronic modular μnmr relaxometer with a 2D digital microfluidic chip for sample management[C], 2015, 302-304.
APA Lei, Ka Meng., Mak, Pui In., Law, Man Kay., & Martins, Rui P. (2015). A thermal-insensitive all-electronic modular μnmr relaxometer with a 2D digital microfluidic chip for sample management. MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 302-304.
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