In this paper, an approach was designed to develop an implantable wideband microstrip patch antenna (MPA) by the high-loss property of human tissue. In order to reduce the detuning effect, an extensive investigation was conducted, demonstrating the effects of high-loss human tissue on the total quality factor (Q _T ), effective relative permittivity, and effective loss tangent of the deeply implanted MPA. To the best of our knowledge, the exact three parameters for the deeply implanted MPA are firstly studied. From the evolutionary point of view, a deeply implanted MPA can be treated as a resonator with the extremely low and stable Q _T . As such, its wide impedance bandwidth can be easily achieved through two inherent radiative modes of the embedded MPA under the high-loss environment. Finally, the proposed MPA will be fabricated and tested, and the final outcomes are consistent with the corresponding simulated results.