Residential College | false |
Status | 已發表Published |
A natural product-like inhibitor of NEDD8-activating enzyme | |
Chung-Hang Leung1; Daniel Shiu-Hin Chan2; Hui Yang2; Ruben Abagyan3; Simon Ming-Yuen Lee4; Guo-Yuan Zhu1; Wang-Fun Fong1; Dik-Lung Ma2 | |
2011 | |
Source Publication | Chemical Communications |
ISSN | 13597345 |
Volume | 47Issue:9Pages:2511 |
Abstract | The natural product-like 6,6″-biapigenin has been identified as only the second inhibitor of NEDD8-activating enzyme using virtual screening. This compound was active in enzyme and cell-based assays, with potency in the micromolar range. © 2011 The Royal Society of Chemistry. |
DOI | 10.1039/c0cc04927a |
URL | View the original |
Language | 英語English |
WOS ID | WOS:000287409800004 |
The Source to Article | Scopus |
Scopus ID | 2-s2.0-79952261355 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | DEPARTMENT OF PHARMACEUTICAL SCIENCES Institute of Chinese Medical Sciences |
Affiliation | 1.Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong 2.Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong 3.Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, USA 4.Institute of Chinese Medical Sciences, University of Macau, Av. Padre Tomás Pereira S.J., Taipa, Macao, China |
Recommended Citation GB/T 7714 | Chung-Hang Leung,Daniel Shiu-Hin Chan,Hui Yang,et al. A natural product-like inhibitor of NEDD8-activating enzyme[J]. Chemical Communications, 2011, 47(9), 2511. |
APA | Chung-Hang Leung., Daniel Shiu-Hin Chan., Hui Yang., Ruben Abagyan., Simon Ming-Yuen Lee., Guo-Yuan Zhu., Wang-Fun Fong., & Dik-Lung Ma (2011). A natural product-like inhibitor of NEDD8-activating enzyme. Chemical Communications, 47(9), 2511. |
MLA | Chung-Hang Leung,et al."A natural product-like inhibitor of NEDD8-activating enzyme".Chemical Communications 47.9(2011):2511. |
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