This paper is concerned with the image-based visual servoing (IBVS) control for uncalibrated camera-robot system with unknown dead-zone constraint, where the uncertain kinematics and dynamics are also considered. The control implementation is achieved by constructing a smooth inverse model for dead-zone-input to eliminate the nonlinear effect resulting from the actuator constraint. A novel adaptive algorithm, which does not require a priori knowledge of the parameter intervals of dead-zone model, is proposed to update the parameter values online, and the dead-zone slopes are not required the same. Furthermore, to accommodate the uncertainties of uncalibrated camera-robot system, adaptation laws are developed to estimate the uncertain parameters, simultaneously avoiding singularity of the image Jacobian matrix. With the full consideration of unknown dead-zone constraint and system uncertainties, an adaptive robust visual tracking control scheme together with dead-zone compensation is subsequently established such that the image tracking error converges to the origin. Based on a 3-DOF manipulator, simulations are conducted to verify the tracking performance of the proposed controller.