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Micro- and nanofabrication NMR technologies for point-of-care medical applications – A review
Dupré,Antoine1; Lei,Ka Meng2,3; Mak,Pui In2,4; Martins,Rui P.2,4,5; Peng,Weng Kung1
Source PublicationMicroelectronic Engineering
ISSN0167-9317
2019-03-15
Abstract

In recent years, significant advances in NMR system miniaturisation (e.g., electronic console, radio-frequency probe, microfluidic-based chip) utilising small footprint permanent magnets (<2 Tesla) have been widely applied for point-of-care medical diagnostic. These include immuno-magnetic labelling-based profiling of tumour cells and biomolecules (DNA and proteins) and the label-free detection of various pathological states such as oxygenation/oxidation level of the blood, malaria screening, and rapid phenotyping of diabetes mellitus. In this contribution we discuss the impact of micro- and nanofabrication technologies and system integration on the miniaturisation of NMR technologies, and the recent advances in NMR-based point-of-care medical diagnosis.

KeywordMicro- And Nanofabrication In Nmr Integrated System Point-of-care Medical Applications
Language英語English
DOI10.1016/j.mee.2019.02.005
URLView the original
Volume209
Pages66-74
WOS IDWOS:000465058900012
WOS SubjectEngineering, Electrical & Electronic ; Nanoscience & Nanotechnology ; Optics ; Physics, Applied
WOS Research AreaEngineering ; Science & Technology - Other Topics ; Optics ; Physics
Indexed BySCIE
Scopus ID2-s2.0-85062329397
Fulltext Access
Citation statistics
Document TypeReview article
CollectionTHE STATE KEY LABORATORY OF ANALOG AND MIXED-SIGNAL VLSI (UNIVERSITY OF MACAU)
Faculty of Science and Technology
INSTITUTE OF MICROELECTRONICS
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Co-First AuthorDupré,Antoine
Corresponding AuthorPeng,Weng Kung
Affiliation1.Precision Medicine - Engineering,Department of Nanoelectronics Engineering,International Iberian Nanotechnology Laboratory,Braga,4715-330,Portugal
2.State Key Laboratory of Analog and Mixed-Signal VLSI,University of Macau,Macao SAR,China
3.School of Engineering and Applied Sciences,Harvard University,Cambridge,02138,United States
4.Instituto Superior Técnico,Universidade de Lisboa,Lisbon,1049-001,Portugal
5.Department of Electrical and Computer Engineering,Faculty of Science and Technology,University of Macau,Macao SAR,China
Recommended Citation
GB/T 7714
Dupré,Antoine,Lei,Ka Meng,Mak,Pui In,et al. Micro- and nanofabrication NMR technologies for point-of-care medical applications – A review[J]. Microelectronic Engineering, 2019, 209, 66-74.
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