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A lanostane aldehyde from Momordica charantia
Panlilio,Bella G.1; MacAbeo,Allan Patrick G.2,3; Knorn,Matthias3; Kohls,Paul3; Richomme,Pascal4; Kouam,Simeon Fogue5; Gehle,Dietmar5; Krohn,Karsten5; Franzblau,Scott G.6; Zhang,Qingwen7,8; Aguinaldo,Ma Alicia M.1,2
2012-09
Source PublicationPhytochemistry Letters
ISSN1874-3900
Volume5Issue:3Pages:682-684
Abstract

A new lanostane aldehyde, charantal (1), was isolated from the ethanolic leaf extract of Momordica charantia together with the known compound, 2,4-bis(2-phenylpropan-2-yl)phenol (2). The structure of compound 1 was elucidated by extensive 1D and 2D NMR and MS experiments. Compound 2 displayed a moderately strong antitubercular activity against Mycobacterium tuberculosis H Rv (MIC = 14 μg/mL) according to the MABA susceptibility assay. 

Keyword2,4-bis(Dimethylbenzyl) Phenol Antitubercular Charantal Lanostane Aldehyde Momordica Charantia
DOI10.1016/j.phytol.2012.07.006
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal
WOS IDWOS:000307596700059
Scopus ID2-s2.0-84865026026
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorAguinaldo,Ma Alicia M.
Affiliation1.Graduate School,University of Santo Tomas,Espana, Manila 1015,Philippines
2.Phytochemistry Laboratory,Research Center for the Natural and Applied Sciences,University of Santo Tomas,España Blvd.,Manila 1015,Philippines
3.Institut für Organische Chemie,Universität Regensburg,Universitätsstr. 31,D-93053 Regensburg,Germany
4.Université d' Angers,SONAS UPRES-EA 921,UFR des Sciences Pharmaceutiques et Ingéniere de la Santé,16 Bd Daviers,F-49100 Angers,France
5.University of Paderborn,Department of Chemistry,Warburgerstr. 100,33098 Paderborn,Germany
6.Institute for Tuberculosis Research,College of Pharmacy,University of Illinois at Chicago,833 S. Wood St.,Chicago, IL 60612-7231,United States
7.State Key Laboratory of Quality Research in Chinese Medicine,University of Macau,Av. Padre Tomás Pereira,Taipa,Macao
8.Institute of Chinese Medical Sciences,University of Macau,Av. Padre Tomás Pereira,Taipa,Macao
Recommended Citation
GB/T 7714
Panlilio,Bella G.,MacAbeo,Allan Patrick G.,Knorn,Matthias,et al. A lanostane aldehyde from Momordica charantia[J]. Phytochemistry Letters, 2012, 5(3), 682-684.
APA Panlilio,Bella G.., MacAbeo,Allan Patrick G.., Knorn,Matthias., Kohls,Paul., Richomme,Pascal., Kouam,Simeon Fogue., Gehle,Dietmar., Krohn,Karsten., Franzblau,Scott G.., Zhang,Qingwen., & Aguinaldo,Ma Alicia M. (2012). A lanostane aldehyde from Momordica charantia. Phytochemistry Letters, 5(3), 682-684.
MLA Panlilio,Bella G.,et al."A lanostane aldehyde from Momordica charantia".Phytochemistry Letters 5.3(2012):682-684.
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