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Status | 已發表Published |
A lanostane aldehyde from Momordica charantia | |
Panlilio,Bella G.1; MacAbeo,Allan Patrick G.2,3; Knorn,Matthias3; Kohls,Paul3; Richomme,Pascal4; Kouam,Simeon Fogue5; Gehle,Dietmar5; Krohn,Karsten5; Franzblau,Scott G.6; Zhang,Qingwen7,8; Aguinaldo,Ma Alicia M.1,2 | |
2012-09 | |
Source Publication | Phytochemistry Letters |
ISSN | 1874-3900 |
Volume | 5Issue:3Pages:682-684 |
Abstract | A new lanostane aldehyde, charantal (1), was isolated from the ethanolic leaf extract of Momordica charantia together with the known compound, 2,4-bis(2-phenylpropan-2-yl)phenol (2). The structure of compound 1 was elucidated by extensive 1D and 2D NMR and MS experiments. Compound 2 displayed a moderately strong antitubercular activity against Mycobacterium tuberculosis H Rv (MIC = 14 μg/mL) according to the MABA susceptibility assay. |
Keyword | 2,4-bis(Dimethylbenzyl) Phenol Antitubercular Charantal Lanostane Aldehyde Momordica Charantia |
DOI | 10.1016/j.phytol.2012.07.006 |
URL | View the original |
Indexed By | SCIE |
Language | 英語English |
WOS Research Area | Plant Sciences ; Pharmacology & Pharmacy |
WOS Subject | Plant Sciences ; Chemistry, Medicinal |
WOS ID | WOS:000307596700059 |
Scopus ID | 2-s2.0-84865026026 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | Institute of Chinese Medical Sciences |
Corresponding Author | Aguinaldo,Ma Alicia M. |
Affiliation | 1.Graduate School,University of Santo Tomas,Espana, Manila 1015,Philippines 2.Phytochemistry Laboratory,Research Center for the Natural and Applied Sciences,University of Santo Tomas,España Blvd.,Manila 1015,Philippines 3.Institut für Organische Chemie,Universität Regensburg,Universitätsstr. 31,D-93053 Regensburg,Germany 4.Université d' Angers,SONAS UPRES-EA 921,UFR des Sciences Pharmaceutiques et Ingéniere de la Santé,16 Bd Daviers,F-49100 Angers,France 5.University of Paderborn,Department of Chemistry,Warburgerstr. 100,33098 Paderborn,Germany 6.Institute for Tuberculosis Research,College of Pharmacy,University of Illinois at Chicago,833 S. Wood St.,Chicago, IL 60612-7231,United States 7.State Key Laboratory of Quality Research in Chinese Medicine,University of Macau,Av. Padre Tomás Pereira,Taipa,Macao 8.Institute of Chinese Medical Sciences,University of Macau,Av. Padre Tomás Pereira,Taipa,Macao |
Recommended Citation GB/T 7714 | Panlilio,Bella G.,MacAbeo,Allan Patrick G.,Knorn,Matthias,et al. A lanostane aldehyde from Momordica charantia[J]. Phytochemistry Letters, 2012, 5(3), 682-684. |
APA | Panlilio,Bella G.., MacAbeo,Allan Patrick G.., Knorn,Matthias., Kohls,Paul., Richomme,Pascal., Kouam,Simeon Fogue., Gehle,Dietmar., Krohn,Karsten., Franzblau,Scott G.., Zhang,Qingwen., & Aguinaldo,Ma Alicia M. (2012). A lanostane aldehyde from Momordica charantia. Phytochemistry Letters, 5(3), 682-684. |
MLA | Panlilio,Bella G.,et al."A lanostane aldehyde from Momordica charantia".Phytochemistry Letters 5.3(2012):682-684. |
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