| Residential College | false |
| Status | 已發表Published |
| A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy | |
Xing, Lei1,2,3,4; Zhang, Jia-Liang1,5; Zhou, Tian-Jiao1; He, Yu-Jing1; Cui, Peng-Fei1; Gong, Jia-Hui1; Sun, Minjie1; Lu, Jin-Jian6 ; Huang, Zhangjian1,4; Jin, Liang1,7 ; Jiang, Hu-Lin1,2,3,4
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| 2018-08-14 | |
| Source Publication | CHEMICAL COMMUNICATIONS
 |
| ISSN | 1359-7345 |
| Volume | 54Issue:63Pages:8737-8740 |
| Abstract | We report a novel and easy-to-fabricate polynuclear nanoparticle based on the collaborative re-assembly of nanoparticles as a robust chemogene co-delivery platform. Specifically, the polynuclear nanoparticle carrying DOX and siBcl-2 exerts remarkable co-delivery efficiency, increases tumour cell apoptosis and inhibits tumour cell proliferation in vitro and in vivo. |
| DOI | 10.1039/c8cc03720e |
| URL | View the original |
| Indexed By | SCIE |
| Language | 英語English |
| WOS Research Area | Chemistry |
| WOS Subject | Chemistry, Multidisciplinary |
| WOS ID | WOS:000446058700015 |
| Publisher | ROYAL SOC CHEMISTRY |
| The Source to Article | WOS |
| Scopus ID | 2-s2.0-85050922957 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | DEPARTMENT OF PHARMACEUTICAL SCIENCES Institute of Chinese Medical Sciences THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU) |
| Corresponding Author | Jin, Liang; Jiang, Hu-Lin |
| Affiliation | 1.State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China 2.Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, China Pharmaceutical University, Nanjing, China 3.Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, Nanjing, China 4.Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing, China 5.Department of Pharmacy, Dong Fang Hospital (Fuzhou General Hospital), Medical College of Xiamen University, Xiamen University, Fouzhou 350025, China 6.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China 7.School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China |
| Recommended Citation GB/T 7714 | Xing, Lei,Zhang, Jia-Liang,Zhou, Tian-Jiao,et al. A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy[J]. CHEMICAL COMMUNICATIONS, 2018, 54(63), 8737-8740. |
| APA | Xing, Lei., Zhang, Jia-Liang., Zhou, Tian-Jiao., He, Yu-Jing., Cui, Peng-Fei., Gong, Jia-Hui., Sun, Minjie., Lu, Jin-Jian., Huang, Zhangjian., Jin, Liang., & Jiang, Hu-Lin (2018). A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy. CHEMICAL COMMUNICATIONS, 54(63), 8737-8740. |
| MLA | Xing, Lei,et al."A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy".CHEMICAL COMMUNICATIONS 54.63(2018):8737-8740. |
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