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Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (SARS-CoV-2): A review and perspective
Yang,Yang; Islam,Md Sahidul; Wang,Jin; Li,Yuan; Chen,Xin
Source PublicationInternational Journal of Biological Sciences
ISSN1449-2288
2020-03-15
Abstract

Currently, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, formerly known as 2019-nCoV, the causative pathogen of Coronavirus Disease 2019 (COVID-19)) has rapidly spread across China and around the world, causing an outbreak of acute infectious pneumonia. No specific anti-virus drugs or vaccines are available for the treatment of this sudden and lethal disease. The supportive care and non-specific treatment to ameliorate the symptoms of the patient are the only options currently. At the top of these conventional therapies, greater than 85% of SARS-CoV-2 infected patients in China are receiving Traditional Chinese Medicine (TCM) treatment. In this article, relevant published literatures are thoroughly reviewed and current applications of TCM in the treatment of COVID-19 patients are analyzed. Due to the homology in epidemiology, genomics, and pathogenesis of the SARS-CoV-2 and SARS-CoV, and the widely use of TCM in the treatment of SARS-CoV, the clinical evidence showing the beneficial effect of TCM in the treatment of patients with SARS coronaviral infections are discussed. Current experiment studies that provide an insight into the mechanism underlying the therapeutic effect of TCM, and those studies identified novel naturally occurring compounds with anti-coronaviral activity are also introduced.

KeywordCoronavirus Pneumonia Sars-cov-2 Traditional Chinese Medicine (Tcm)
Language英語English
DOI10.7150/ijbs.45538
URLView the original
Volume16
Issue10
Pages1708-1717
WOS IDWOS:000522973800005
WOS SubjectBiochemistry & Molecular Biology ; Biology
WOS Research AreaBiochemistry & Molecular Biology ; Life Sciences & Biomedicine - Other Topics
Indexed BySCIE
Scopus ID2-s2.0-85082634876
Fulltext Access
Citation statistics
Document TypeReview article
CollectionTHE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Institute of Chinese Medical Sciences
Corresponding AuthorChen,Xin
AffiliationState Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,999078,Macao
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Yang,Yang,Islam,Md Sahidul,Wang,Jin,et al. Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (SARS-CoV-2): A review and perspective[J]. International Journal of Biological Sciences, 2020, 16(10), 1708-1717.
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