Residential College | false |
Status | 已發表Published |
In vitro anti-platelet aggregation effects of fourteen fruits and vegetables | |
Cen Chen1; Qian Zhang1; Feng-Qin Wang1; Chun-Hong Li1; Yuan-Jia Hu2![]() ![]() | |
2019-01 | |
Source Publication | PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
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ISSN | 1011-601X |
Volume | 32Issue:1Pages:185-195 |
Abstract | In the present study, the anti-platelet aggregation activity of 14 vegetables and fruits was tested in vitro. The aqueous, 90% ethanol and ethyl acetate extracts, as well as concentrated juices of 14 foods (fruits and vegetables) were prepared, and the anti-platelet aggregation activity of those extracts was analyzed on a platelet aggregation analyzer in vitro with adenosine 5’-diphosphate (ADP), bovine thrombin (THR) and arachidonic acid (AA) as aggregation inducers, respectively. Aspirin (ASP) was used as the positive control. A number of the tested foods had inhibitory effects in concentration-dependent manner on platelet aggregations induced by various agonists. Especially, some foods such as lemon, leek, garlic, scallion, ginger, tomato and grapefruit showed good anti-platelet aggregation effect similar or higher than that of positive control group i.e. aspirin (ASP). The results of present study provide scientific reference for reasonable selection of daily dietary with supplementary curative effects or prevention of cardiovascular diseases (CVD). |
Keyword | Anti-platelet Aggregation Adenosine 5'-diphosphate Bovine Thrombin Arachidonic Acid Food Materials |
Indexed By | SCIE |
Language | 英語English |
WOS Research Area | Pharmacology & Pharmacy |
WOS Subject | Pharmacology & Pharmacy |
WOS ID | WOS:000460846900026 |
Scopus ID | 2-s2.0-85061744785 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | Institute of Chinese Medical Sciences |
Corresponding Author | Feng-Qing Yang |
Affiliation | 1.School of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China 2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, PR China |
Recommended Citation GB/T 7714 | Cen Chen,Qian Zhang,Feng-Qin Wang,et al. In vitro anti-platelet aggregation effects of fourteen fruits and vegetables[J]. PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 32(1), 185-195. |
APA | Cen Chen., Qian Zhang., Feng-Qin Wang., Chun-Hong Li., Yuan-Jia Hu., Zhi-Ning Xia., & Feng-Qing Yang (2019). In vitro anti-platelet aggregation effects of fourteen fruits and vegetables. PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 32(1), 185-195. |
MLA | Cen Chen,et al."In vitro anti-platelet aggregation effects of fourteen fruits and vegetables".PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES 32.1(2019):185-195. |
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