A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes

doi:10.1039/c9cc02189b

UM > Institute of Chinese Medical Sciences

Residential College	false
Status	已發表Published
	A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes
	Wu, C 1; Wu, KJ2 ; Liu, JB 1,3; Zhou, XM 4; Leung, CH2 ; Ma, DL 1
	2019-06-07
Source Publication	CHEMICAL COMMUNICATIONS
ISSN	1359-7345
Volume	55 Issue:45 Pages:6353-6356
Abstract	We have designed for the first time a dual-functional luminescent probe and inhibitor of neuraminidase (NA), a key influenza target. The lead iridium(III) complex exhibited enhanced inhibition against NA compared to the FDA-approved antiviral drug, oseltamivir, and could detect NA even in the presence of an autofluorescent background.
DOI	10.1039/c9cc02189b
Indexed By	SCIE
Language	英語English
WOS Research Area	Chemistry
WOS Subject	Chemistry, Multidisciplinary
WOS ID	WOS:000471038300027
Scopus ID	2-s2.0-85066440036
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Corresponding Author	Leung, CH; Ma, DL
Affiliation	1.Hong Kong Baptist Univ, Dept Chem, Kowloon, Hong Kong, Peoples R China 2.University of Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China 3.Jiangxi Univ Sci & Technol, Sch Met & Chem Engn, Ganzhou, Peoples R China 4.South China Normal Univ, Coll Biophoton, MOE Key Lab Laser Life Sci, Guangzhou, Guangdong, Peoples R China
Corresponding Author Affilication	University of Macau
Recommended Citation GB/T 7714	Wu, C,Wu, KJ,Liu, JB,et al. A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes[J]. CHEMICAL COMMUNICATIONS, 2019, 55(45), 6353-6356.
APA	Wu, C., Wu, KJ., Liu, JB., Zhou, XM., Leung, CH., & Ma, DL (2019). A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes. CHEMICAL COMMUNICATIONS, 55(45), 6353-6356.
MLA	Wu, C,et al."A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes".CHEMICAL COMMUNICATIONS 55.45(2019):6353-6356.

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