The trajectory of bereaved people's psychological symptoms has not been fully understood. This study examined how the effects of bereavement change over time, as moderated by a belief in fate control, which is the recognition that events are predetermined by some impersonal forces, and that there are ways to influence these fated outcomes. In this controlled group prospective study, 2,077 Chinese responded to six waves of survey. They completed the fatecontrol scale at Wave 1, and the Depression Anxiety Stress Scales at Waves 2 through 6. At Wave 3, 198 reported having lost a family member recently. Fatecontrol predicted depressive mood at all four post-loss measurements, anxiety at three post-loss measurements, and stress at two post-loss measurements. Bereavement status predicted the psychological symptoms only at Wave 3. Latent growth modeling showed that the bereaved people's mood trajectory depended on whether they believed in fate. In particular, there was an interaction effect between bereavement status and fate control on the latent linear growth factor, and also on the latent quadratic growth factor, of depressive mood. The harmful effects of holding a strong belief in fate control on depressive mood are aggravated by a loss experience.