This paper presents the preliminary results of a study for the liquefaction potential of the sand fill in Macao. The study includes the analysis of SPT (N) distributions. Following the procedure developed by Seed et al. and recommended by NCEER workshop, the cyclic resistance ratio (CRR) and cyclic stress ratio (CSR) were evaluated based on the SPT N values and the relevant seismic data such as the Macao peak ground accelerations. In addition, reliability analysis was performed to take into account the variability of SPT N values, and the probability for the factor of safety that are less than 1.0 was also assessed. It was found that sand fills in Macao have potential for soil liquefaction, and the sandy soils from 8 to 10 m below the reclaimed ground surface may be the most susceptible to liquefaction in Macao.