Locations of images have been widely used in many application scenarios for large geotagged image corpora. As to images that are not geographically tagged, we estimate their locations with the help of the large geotagged image set by content-based image retrieval. Bag-of-words image representation has been utilized widely. However, the individual visual word-based image retrieval approach is not effective in expressing the salient relationships of image region. In this paper, we present an image location estimation approach by multisaliency enhancement. We first extract region-of-interests (ROIs) by mean-shift clustering on the visual words and salient map of the image based on which we further determine the importance of the ROI. Then, we describe each ROI by the spatial descriptors of visualwords. Finally, regionbased visual phrases are generated to further enhance the saliency in image location estimation. Experiments show the effectiveness of our proposed approach.