In this paper, we consider the problem of estimating the Laplace transform of volatility within a fixed time interval [0, T] using high frequency sampling, where we assume that the discretized observations of the latent process are contaminated by microstructure noise. We employ the pre-averaging approach to deal with the effect of microstructure noise. Under the high frequency scenario, we obtain a consistent estimator whose convergence rate is ∆−1/4 n , which is known as the optimal convergence rate of the estimation of integrated volatility functionals under presence of microstructure noise. The related central limit theorem is established. The simulation studies justify the finite sample performance of the proposed estimator.