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A Thermal-Insensitive All-Electronic Modular µNMR Relaxometer with a 2D Digital Microfluidic Chip for Sample Management
Ka Meng Lei1; Pui-In Mak1; Man-Kay Law1; R.P. Martins1,2
2015
Conference Name19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015)
Source Publication19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015)
Conference Date25 – 29 October 2015
Conference PlaceGyeongju, Korea
Abstract

Presented is an electronic-automated micro-Nuclear Magnetic Resonance (μNMR) relaxometer with multi-sample droplet management capability for Point-of-Care diagnostics. Constraints of sample handling inside the cramped magnet are overcome by integration of microfluidic and microelectronic technologies. The two-dimensional digital microfluidic (DMF) device with sample location detecting capability enables automatic sample manipulation. Additionally, a calibrator ensures precise proton excitation against ambient temperature (18-30°C). Experiments have corroborated auto-handling and identification of two targets within 2.2 minutes, indicating it as a promising tool for Point-of-Care application.

KeywordNuclear Magnetic Resonance Biosensor Digital Microfluidic
URLView the original
Language英語English
Document TypeConference paper
CollectionINSTITUTE OF MICROELECTRONICS
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Affiliation1.State-Key Laboratory of Analog and Mixed-Signal VLSI, University of Macau, China
2.On leave from Instituto Superior Técnico, Universidade de Lisboa, Portugal
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Ka Meng Lei,Pui-In Mak,Man-Kay Law,et al. A Thermal-Insensitive All-Electronic Modular µNMR Relaxometer with a 2D Digital Microfluidic Chip for Sample Management[C], 2015.
APA Ka Meng Lei., Pui-In Mak., Man-Kay Law., & R.P. Martins (2015). A Thermal-Insensitive All-Electronic Modular µNMR Relaxometer with a 2D Digital Microfluidic Chip for Sample Management. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015).
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