The computation of grain burning surface regression plays a very important role in the internal ballistic performance evaluation of solid rocket motor, however, the traditional methods such as geometry-based one could not handle the self-intersection and characteristic geometric element disappearing problems. This paper presents an effective and efficient framework to simulate 3D grain burning surface regression with level set method which is combined with Fast Marching technique to constrain the calculation area only around the burning surface. At last, a typical grain example is given by our framework to verify our method's effectiveness and efficiency. © (2012) Trans Tech Publications.