| Residential College | false |
| Status | 已發表Published |
| Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy | |
| Zhang, Junjie1; Liu, Zilu1; Zhang, Zhijing1; Yang, Hui1; Wang, Hui1; Yang, Zhenlu2; Xu, Yunjian3,4; Li, Shengke5; Yang, Dongliang6 | |
| 2024-11-18 | |
| Source Publication | ACS Applied Bio Materials
 |
| Volume | 7Issue:11Pages:7133-7169 |
| Abstract | Cancer remains a formidable challenge, inflicting profound physical, psychological, and financial burdens on patients. In this context, silica-based nanomaterials have garnered significant attention for their potential in tumor imaging and therapy owing to their exceptional properties, such as biocompatibility, customizable porosity, and versatile functionalization capabilities. This review meticulously examines the latest advancements in the application of silica-based nanomaterials for tumor imaging and therapy. It underscores their potential in enhancing various cancer imaging modalities, including fluorescence imaging, magnetic resonance imaging, computed tomography, positron emission tomography, ultrasound imaging, and multimodal imaging approaches. Moreover, the review delves into their therapeutic efficacy in chemotherapy, radiotherapy, phototherapy, immunotherapy, gas therapy, sonodynamic therapy, chemodynamic therapy, starvation therapy, and gene therapy. Critical evaluations of the biosafety profiles and degradation pathways of these nanomaterials within biological environments are also presented. By discussing the current challenges and prospects, this review aims to provide a nuanced perspective on the clinical translation of silica-based nanomaterials, thereby highlighting their promise in revolutionizing cancer diagnostics, enabling real-time monitoring of therapeutic responses, and advancing personalized medicine. |
| Keyword | biocompatibility cancer therapy drug delivery silica-based nanomaterials tumor imaging |
| DOI | 10.1021/acsabm.4c01318 |
| URL | View the original |
| Language | 英語English |
| Scopus ID | 2-s2.0-85208181901 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | University of Macau |
| Affiliation | 1.School of Fundamental Sciences, Bengbu Medical University, Bengbu, 233030, China 2.Department of Radiology, Guizhou Provincial People’s Hospital, Guiyang, Guizhou, 550000, China 3.School of Radiology, Shandong First Medical University, Shandong Academy of Medical Sciences, Tai’an, 271000, China 4.Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, 250000, China 5.Macao Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, 999078, Macao 6.Key Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM), School of Physical and Mathematical Sciences, Nanjing Tech University (NanjingTech), Nanjing, 211816, China |
| Recommended Citation GB/T 7714 | Zhang, Junjie,Liu, Zilu,Zhang, Zhijing,et al. Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy[J]. ACS Applied Bio Materials, 2024, 7(11), 7133-7169. |
| APA | Zhang, Junjie., Liu, Zilu., Zhang, Zhijing., Yang, Hui., Wang, Hui., Yang, Zhenlu., Xu, Yunjian., Li, Shengke., & Yang, Dongliang (2024). Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy. ACS Applied Bio Materials, 7(11), 7133-7169. |
| MLA | Zhang, Junjie,et al."Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy".ACS Applied Bio Materials 7.11(2024):7133-7169. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment