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Occurrence and potential risks of pharmaceutical contamination in global Estuaries: A critical review and analysis
Adedipe, Demilade T.1; Chen, Chong1; Lai, Racliffe Weng Seng2; Xu, Shaopeng1; Luo, Qiong1; Zhou, Guang Jie3; Boxall, Alistair4; Brooks, Bryan W.5; Doblin, Martina A.6,7; Wang, Xinhong8; Wang, Juying9; Leung, Kenneth Mei Yee1,10
2024-10-01
Source PublicationEnvironment International
ISSN0160-4120
Volume192
AbstractInput of pollutants to estuaries is one of the major threats to marine biodiversity and fishery resources, and pharmaceuticals are one of the most important contaminants of emerging concern in aquatic ecosystems. To synthesize pharmaceutical pollution levels in estuaries over the past 20 years from a global perspective, this review identified 3229 individual environmental occurrence data for 239 pharmaceuticals across 91 global estuaries distributed in 26 countries. The highest cumulative weighted average concentration level (WACL) of all detected pharmaceuticals in estuarine water was observed in Africa (145,461.86 ng/L), with 30 pharmaceuticals reported. North America (24,316.39 ng/L) was ranked second in terms of WACL, followed by South America (20,784.13 ng/L), Asia (5958.38 ng/L), Europe (4691.23 ng/L), and Oceania (2916.32 ng/L). Carbamazepine, diclofenac, and paracetamol were detected in all continents. A total of 41 functional categories of pharmaceuticals were identified, and analgesics, antibiotics, and stimulants were amongst the most ubiquitous groups in estuaries worldwide. Although many pharmaceuticals were observed to present lower than or equal to moderate ecological risk, 34 pharmaceuticals were identified with high or very high ecological risks in at least one continent. Pharmaceutical pollution in estuaries was positively correlated with regional unemployment and poverty ratios, but negatively correlated with life expectancy and GDP per capita. There are some limitations that may affect this synthesis, such as comparability of the sampling and pretreatment methodology, differences in the target pharmaceuticals for monitoring, and potentially limited number and diversity of estuaries covered, which prompt us to standardize methods for monitoring these pharmaceutical contaminants in future global studies.
KeywordContaminants of emerging concern Ecological risk Meta-analysis Socio-economic impact Spatial distribution
DOI10.1016/j.envint.2024.109031
URLView the original
Language英語English
Scopus ID2-s2.0-85204710232
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Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.State Key Laboratory of Marine Pollution and Department of Chemistry, City University of Hong Kong, Kowloon, Hong Kong, China
2.Department of Ocean Science and Technology, Faculty of Science and Technology, The University of Macau, Macau, China
3.Department of Ecology and Institute of Hydrobiology, Jinan University, Guangzhou, China
4.Department of Environment and Geography, University of York, York, YO10 5DD, United Kingdom
5.Department of Environmental Science, Baylor University, Waco, United States
6.Sydney Institute of Marine Science, Mosman, Australia
7.Climate Change Cluster, University of Technology Sydney, Ultimo, Australia
8.State Key Laboratory of Marine Environmental Science, College of the Environment & Ecology, Xiamen University, Xiamen, China
9.National Marine Environment Monitoring Center, Liaoning, China
10.School of Energy and Environment, City University of Hong Kong, Kowloon, Hong Kong, China
Recommended Citation
GB/T 7714
Adedipe, Demilade T.,Chen, Chong,Lai, Racliffe Weng Seng,et al. Occurrence and potential risks of pharmaceutical contamination in global Estuaries: A critical review and analysis[J]. Environment International, 2024, 192.
APA Adedipe, Demilade T.., Chen, Chong., Lai, Racliffe Weng Seng., Xu, Shaopeng., Luo, Qiong., Zhou, Guang Jie., Boxall, Alistair., Brooks, Bryan W.., Doblin, Martina A.., Wang, Xinhong., Wang, Juying., & Leung, Kenneth Mei Yee (2024). Occurrence and potential risks of pharmaceutical contamination in global Estuaries: A critical review and analysis. Environment International, 192.
MLA Adedipe, Demilade T.,et al."Occurrence and potential risks of pharmaceutical contamination in global Estuaries: A critical review and analysis".Environment International 192(2024).
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