Due to the needs of public health, the importance of medicines has become increasingly prominent. However, the high price of imported medicines not only prevents people from getting good treatment but also prevents medicines from playing their supposed role of curing diseases and saving lives. However, the medicines patent compulsory licensing system can effectively help people to tackle this issue. Therefore, it is essential that people should study the medicines’ patent compulsory licensing. Discuss the compulsory Permission of pharmaceutical patents originate an international viewpoint using literature research and comparative analysis. First, sort out the regulations and defects of China’s compulsory licensing of medicines patents, then analyze the regulations on compulsory licensing of medicines patents outside the region. On this basis, based on the defects of China’s medicines patent compulsory licensing, combined with foreign experience, corresponding improvement suggestions are put forward to provide a helpful reference for China’s medicines patent compulsory licensing system.