| Residential College | false |
| Status | 已發表Published |
| Protein nanoparticles as drug delivery systems for cancer theranostics | |
| Hua, Yue1; Qin, Zibo2; Gao, Lin2; Zhou, Mei2; Xue, Yonger3; Li, Yue4; Xie, Jinbing2 | |
| 2024-07-01 | |
| Source Publication | Journal of Controlled Release
 |
| ISSN | 0168-3659 |
| Volume | 371Pages:429-444 |
| Abstract | Protein-based nanoparticles have garnered significant attention in theranostic applications due to their superior biocompatibility, exceptional biodegradability and ease of functionality. Compared to other nanocarriers, protein-based nanoparticles offer additional advantages, including biofunctionality and precise molecular recognition abilities, which make them highly effective in navigating complex biological environments. Moreover, proteins can serve as powerful tools with self-assembling structures and reagents that enhance cell penetration. And their derivation from abundant renewable sources and ability to degrade into harmless amino acids further enhance their suitability for biomedical applications. However, protein-based nanoparticles have so far not realized their full potential. In this review, we summarize recent advances in the use of protein nanoparticles in tumor diagnosis and treatment and outline typical methods for preparing protein nanoparticles. The review of protein nanoparticles may provide useful new insights into the development of biomaterial fabrication. |
| Keyword | cancer imaging cancer therapy drug delivery Protein nanoparticles |
| DOI | 10.1016/j.jconrel.2024.06.004 |
| URL | View the original |
| Language | 英語English |
| Scopus ID | 2-s2.0-85195298207 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | University of Macau |
| Affiliation | 1.Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250000, China 2.Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology; Basic Medicine Research and Innovation Center of Ministry of Education; Department of Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, 87 Dingjiaqiao Road, 210009, China 3.Center for BioDelivery Sciences, School of Pharmacy, Shanghai, Shanghai Jiao Tong University, 800 Dongchuan Rd, 200240, China 4.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR, 999078, China |
| Recommended Citation GB/T 7714 | Hua, Yue,Qin, Zibo,Gao, Lin,et al. Protein nanoparticles as drug delivery systems for cancer theranostics[J]. Journal of Controlled Release, 2024, 371, 429-444. |
| APA | Hua, Yue., Qin, Zibo., Gao, Lin., Zhou, Mei., Xue, Yonger., Li, Yue., & Xie, Jinbing (2024). Protein nanoparticles as drug delivery systems for cancer theranostics. Journal of Controlled Release, 371, 429-444. |
| MLA | Hua, Yue,et al."Protein nanoparticles as drug delivery systems for cancer theranostics".Journal of Controlled Release 371(2024):429-444. |
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